Tipranavir

Generic Name
Tipranavir
Brand Names
Aptivus
Drug Type
Small Molecule
Chemical Formula
C31H33F3N2O5S
CAS Number
174484-41-4
Unique Ingredient Identifier
ZZT404XD09
Background

Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. Tipranavir and ritonavir are coadministered to treat HIV.

Indication

For combination antiretroviral treatment of HIV-1 infected adult patients with evidence of viral replication, who are highly treatment-experienced or have HIV-1 strains resistant to multiple protease inhibitors.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected Patients

Phase 2
Completed
Conditions
First Posted Date
2003-03-21
Last Posted Date
2023-12-01
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
328
Registration Number
NCT00056641
Locations
🇺🇸

UT Southwestern, Dallas, Texas, United States

🇨🇦

Toronto General Hospital, Toronto, Ontario, Canada

🇩🇪

Boehringer Ingelheim Investigational Site, Stuttgart, Germany

and more 78 locations

Randomized Evaluation of Strategic Intervention in Multidrug Resistant Patients With Tipranavir (RESIST)

First Posted Date
2003-02-10
Last Posted Date
2014-07-02
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
630
Registration Number
NCT00054717
Locations
🇺🇸

1182.12.9 Boehringer Ingelheim Investigational Site, Berkeley, California, United States

🇺🇸

1182.12.7 Boehringer Ingelheim Investigational Site, Norwalk, Connecticut, United States

🇺🇸

1182.12.1 Boehringer Ingelheim Investigational Site, Los Angeles, California, United States

and more 114 locations
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