Glimepiride

Generic Name
Glimepiride
Brand Names
Duetact, Tandemact
Drug Type
Small Molecule
Chemical Formula
C24H34N4O5S
CAS Number
93479-97-1
Unique Ingredient Identifier
6KY687524K
Background

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure a...

Indication

Glimepiride is indicated for the management of type 2 diabetes in adults as an adjunct to diet and exercise to improve glycemic control as monotherapy.
...

Associated Conditions
Type 2 Diabetes Mellitus
Associated Therapies
-

Continuous Glucose Monitoring System (CGMS) in Type 2 Diabetic Patients Inadequately Controlled by Metformine Monotherapy; Analyze of Glycemic Profile Before and After Association of Glimepiride

Phase 4
Completed
Conditions
First Posted Date
2008-03-12
Last Posted Date
2008-03-28
Lead Sponsor
Sanofi
Target Recruit Count
43
Registration Number
NCT00633425
Locations
🇫🇷

Sanofi-Aventis, Paris, France

Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

First Posted Date
2008-02-25
Last Posted Date
2014-01-29
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
1560
Registration Number
NCT00622284
Locations
🇺🇸

1218.20.10030 Boehringer Ingelheim Investigational Site, Topeka, Kansas, United States

🇺🇸

1218.20.10035 Boehringer Ingelheim Investigational Site, Los Angeles, California, United States

🇺🇸

1218.20.10003 Boehringer Ingelheim Investigational Site, Chula Vista, California, United States

and more 218 locations

The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes Mellitus

First Posted Date
2008-02-21
Last Posted Date
2017-03-08
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
49
Registration Number
NCT00620282
Locations
🇺🇸

Novo Nordisk Investigational Site, Rochester, Minnesota, United States

Efficacy and Safety of Biphasic Insulin Aspart 30 in Combination With Metformin in Type 2 Diabetes

Phase 4
Completed
Conditions
First Posted Date
2008-02-21
Last Posted Date
2017-01-06
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
260
Registration Number
NCT00619697
Locations
🇸🇮

Novo Nordisk Investigational Site, Maribor, Slovenia

Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes

First Posted Date
2008-02-13
Last Posted Date
2017-03-08
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
929
Registration Number
NCT00614120
Locations
🇰🇷

Novo Nordisk Investigational Site, Suwon, Korea, Republic of

Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-02-06
Last Posted Date
2014-12-11
Lead Sponsor
Vanderbilt University
Target Recruit Count
32
Registration Number
NCT00608179

Pharmacokinetic Drug Interaction Study With Dapagliflozin and Glimepiride in Healthy Subjects

First Posted Date
2007-11-22
Last Posted Date
2016-10-17
Lead Sponsor
AstraZeneca
Target Recruit Count
11
Registration Number
NCT00562250
Locations
🇦🇷

Local Institution, Vicente Lopez, Buenos Aires, Argentina

Insulin Glargine (Lantus) vs Sulfonylurea (SU) for BETA Cell Function (BETA Study)

First Posted Date
2007-11-21
Last Posted Date
2012-07-17
Lead Sponsor
Sanofi
Target Recruit Count
75
Registration Number
NCT00562172
Locations
🇰🇷

Sanofi-aventis, Seoul, Korea, Republic of

Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes

First Posted Date
2007-05-04
Last Posted Date
2017-03-01
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
174
Registration Number
NCT00469586
Locations
🇹🇷

Novo Nordisk Investigational Site, Konya, Turkey

Comparison of Biphasic Insulin Aspart 30 Versus Insulin Glargine Both in Combination With Metformin and Glimepiride in Subjects With Type 2 Diabetes

First Posted Date
2007-05-04
Last Posted Date
2017-02-23
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
480
Registration Number
NCT00469092
Locations
🇸🇪

Novo Nordisk Investigational Site, Stockholm, Sweden

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