Glimepiride
- Generic Name
- Glimepiride
- Brand Names
- Duetact, Tandemact
- Drug Type
- Small Molecule
- Chemical Formula
- C24H34N4O5S
- CAS Number
- 93479-97-1
- Unique Ingredient Identifier
- 6KY687524K
- Background
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure a...
- Indication
Glimepiride is indicated for the management of type 2 diabetes in adults as an adjunct to diet and exercise to improve glycemic control as monotherapy.
...
- Associated Conditions
- Type 2 Diabetes Mellitus
- Associated Therapies
- -
Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2023-08-04
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 92
- Registration Number
- NCT05975528
- Locations
- 🇰🇷
Yonsei University College of Medicine, Seoul, Korea, Republic of
Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes
- First Posted Date
- 2022-12-23
- Last Posted Date
- 2023-03-08
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT05663736
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of
The Effects of Glimepiride in Patients With Type 2 Diabetes and Chronic Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2022-09-14
- Last Posted Date
- 2022-11-16
- Lead Sponsor
- Dao Wen Wang
- Target Recruit Count
- 1018
- Registration Number
- NCT05538819
- Locations
- 🇨🇳
Tongji Hospital, Wuhan, Hubei, China
Bioequivalence Study of 3 mg Glimepiride Tablet in Indonesia Healthy Subjects
- First Posted Date
- 2022-07-21
- Last Posted Date
- 2022-07-21
- Lead Sponsor
- PT Harsen Laboratories
- Target Recruit Count
- 34
- Registration Number
- NCT05468879
- Locations
- 🇮🇩
PT Pharma Metric Labs, Jakarta, DKI Jakarta, Indonesia
The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency Diabetes
- Conditions
- Interventions
- First Posted Date
- 2022-05-23
- Last Posted Date
- 2022-05-23
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 192
- Registration Number
- NCT05386186
- Locations
- 🇨🇳
Peking University People's Hospital, Beijing, Please Select, China
Replication of the LEAD-2 Diabetes Trial in Healthcare Claims Data
- First Posted Date
- 2021-12-17
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 3474
- Registration Number
- NCT05162183
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Replication of the GRADE Diabetes Trial in Healthcare Claims Data
- First Posted Date
- 2021-10-29
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 6403
- Registration Number
- NCT05099198
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Glimepiride, Alogliptin and Alogliptin+Pioglitazone Combination
- Conditions
- Interventions
- First Posted Date
- 2020-07-14
- Last Posted Date
- 2020-10-22
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 99
- Registration Number
- NCT04470310
Omega 3 Fatty Acids on Serum Irisin and Sirtuin-1 in Type 2 Diabetic Mellitus Patients Treated With Glimepiride
- Conditions
- Interventions
- First Posted Date
- 2019-04-17
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- Damanhour University
- Target Recruit Count
- 70
- Registration Number
- NCT03917940
- Locations
- 🇪🇬
Damanhour Medical National Institute, Damanhūr, El-Bahairah, Egypt
Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy
- Conditions
- Interventions
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2021-05-11
- Lead Sponsor
- Lexicon Pharmaceuticals
- Target Recruit Count
- 954
- Registration Number
- NCT03332771
- Locations
- 🇺🇸
Investigational Site Number 8407074, Bradenton, Florida, United States
🇺🇸Investigational Site Number 8407111, Dallas, Texas, United States
🇺🇸Investigational Site Number 8407078, Carmichael, California, United States
Drug Development Updates
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