Corticotropin
未知生产厂商
Corticotropin is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Corticotropin is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
As a diagnostic aid (adrenocortical function), corticotropin combines with a specific receptor on the adrenal cell plasma membrane. In patients with normal adrenocortical function, it stimulates the initial reaction involved in the synthesis of adrenal steroids (including cortisol, cortisone, weak androgenic substances, and a limited quantity of aldosterone) from cholesterol by increasing the quantity of cholesterol within the mitochondria. Corticotropin does not significantly increase serum cortisol concentrations in patients with primary adrenocortical insufficiency (Addison's disease). The mechanism of action of corticotropin in the treatment of infantile myoclonic seizures is unknown.
For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency. Purified corticotropin for injection is indicated for a variety of allergic and autoimmune conditions.
共 24 项相关疾病
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
