MedPath

Fisetin

Generic Name
Fisetin
Drug Type
Small Molecule
Chemical Formula
C15H10O6
CAS Number
528-48-3
Unique Ingredient Identifier
OO2ABO9578

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

Phase 1
Not yet recruiting
Conditions
Healthy
Multimorbidity
Interventions
Drug: Placebo
First Posted Date
2024-05-29
Last Posted Date
2024-08-28
Lead Sponsor
Ove Andersen
Target Recruit Count
60
Registration Number
NCT06431932

Fisetin to Reduce Senescence and Mobility Impairment in PAD

Phase 2
Recruiting
Conditions
Peripheral Arterial Disease
Aging
Peripheral Vascular Diseases
Walking, Difficulty
Claudication
Interventions
Drug: Placebo
First Posted Date
2024-05-06
Last Posted Date
2024-10-08
Lead Sponsor
Northwestern University
Target Recruit Count
34
Registration Number
NCT06399809
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

Prevention of Frailty with Fisetin and Exercise (PROFFi) in Breast Cancer Survivors

Phase 2
Recruiting
Conditions
Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) V8
Anatomic Stage II Breast Cancer AJCC V8
Anatomic Stage III Breast Cancer AJCC V8
Early Stage Breast Carcinoma
Interventions
Procedure: Biospecimen Collection
Other: Educational Intervention
Other: Exercise Intervention
Other: Physical Performance Testing
Drug: Placebo Administration
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2023-11-02
Last Posted Date
2024-12-20
Lead Sponsor
Jonsson Comprehensive Cancer Center
Target Recruit Count
164
Registration Number
NCT06113016
Locations
🇺🇸

UCLA Health Cancer Care in Alhambra, Alhambra, California, United States

🇺🇸

UCLA Health Beverly Hills Primary & Specialty Care, Beverly Hills, California, United States

🇺🇸

UCLA Health Burbank Primary & Specialty Care, Burbank, California, United States

and more 3 locations

Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors

Phase 2
Recruiting
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Interventions
Procedure: Biospecimen Collection
Drug: Placebo Administration
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2022-10-27
Last Posted Date
2025-05-13
Lead Sponsor
Jonsson Comprehensive Cancer Center
Target Recruit Count
88
Registration Number
NCT05595499
Locations
🇺🇸

UCLA Health Cancer Care in Alhambra, Alhambra, California, United States

🇺🇸

UCLA Health Beverly Hills Primary & Specialty Care, Beverly Hills, California, United States

🇺🇸

UCLA Health Burbank Primary & Specialty Care, Burbank, California, United States

and more 4 locations

Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiency

Phase 2
Conditions
Common Variable Immunodeficiency
Interstitial Lung Disease Due to Systemic Disease
Interventions
Drug: Placebo
First Posted Date
2022-10-25
Last Posted Date
2025-05-06
Lead Sponsor
Avni Joshi
Target Recruit Count
20
Registration Number
NCT05593588
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair

Phase 2
Withdrawn
Conditions
Meniscus Tear
Meniscus; Derangement
Meniscus Lesion
Meniscus Disorder
Interventions
Drug: Placebo oral capsule
First Posted Date
2022-08-18
Last Posted Date
2025-05-08
Lead Sponsor
Austin V Stone
Target Recruit Count
38
Registration Number
NCT05505747
Locations
🇺🇸

UK Healthcare at Turfland, Lexington, Kentucky, United States

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

Phase 2
Withdrawn
Conditions
Knee Osteoarthritis
Obese
Depression
Interventions
Drug: Placebo oral capsule
Behavioral: GetHealthy-OA mind-body program
Behavioral: Health education booklet
First Posted Date
2022-08-01
Last Posted Date
2023-05-01
Lead Sponsor
Cale Andrew Jacobs, PhD
Registration Number
NCT05482672
Locations
🇺🇸

UK HealthCare Joint Reconstruction and Replacement, Lexington, Kentucky, United States

🇺🇸

UK Healthcare at Turfland, Lexington, Kentucky, United States

A Study of Fisetin to Treat Carpal Tunnel Syndrome

Phase 2
Active, not recruiting
Conditions
Carpal Tunnel Syndrome
Interventions
First Posted Date
2022-06-13
Last Posted Date
2025-01-23
Lead Sponsor
Peter C. Amadio, M.D.
Target Recruit Count
40
Registration Number
NCT05416515
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

Phase 1
Active, not recruiting
Conditions
Femoroacetabular Impingement
Interventions
Drug: Placebo
First Posted Date
2021-08-30
Last Posted Date
2024-04-16
Lead Sponsor
Steadman Philippon Research Institute
Target Recruit Count
68
Registration Number
NCT05025956
Locations
🇺🇸

The Steadman Clinic, Vail, Colorado, United States

Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Phase 1
Active, not recruiting
Conditions
Osteoarthritis, Knee
Interventions
First Posted Date
2021-03-25
Last Posted Date
2024-04-16
Lead Sponsor
Steadman Philippon Research Institute
Target Recruit Count
100
Registration Number
NCT04815902
Locations
🇺🇸

The Steadman Clinic, Vail, Colorado, United States

© Copyright 2025. All Rights Reserved by MedPath