Glucose
- Generic Name
- Glucose
- Brand Names
- Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One
- Drug Type
- Small Molecule
- Unique Ingredient Identifier
- IY9XDZ35W2
- Background
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.
- Indication
Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.
- Associated Conditions
- Arrhythmia, Caloric Deficit, Edema of the cerebrum, Hypoglycemia, Metabolic Alkalosis
- Associated Therapies
- Blood Specimen Collection, Electrolyte replacement, Nutritional supplementation, Parenteral Nutrition, Parenteral rehydration therapy, Plasmapheresis, Positive cardiac inotropic effect, Total parenteral nutrition therapy, Urine alkalinization therapy, Fluid and electrolyte maintenance therapy
Milk as Treatment for Hypoglycemia
- Conditions
- Type 1 Diabetes
- First Posted Date
- 2008-03-26
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- Creighton University
- Registration Number
- NCT00643110
- Locations
- 🇺🇸
Creighton Diabetes Center, Omaha, Nebraska, United States
Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC)
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Drug: 5% Dextrose Solution
- First Posted Date
- 2008-02-18
- Last Posted Date
- 2024-05-03
- Lead Sponsor
- Imunon
- Target Recruit Count
- 701
- Registration Number
- NCT00617981
- Locations
- 🇹🇭
Siriraj Hospital, Bangkok, Thailand
🇨🇳Sun Yat-Sen University Cancer Center, Guangzhou, China
🇺🇸Mayo Clinic - Jacksonville, Florida, Jacksonville, Florida, United States
Beta-Cell Function After Near-Normalisation of Blood Glucose
- Conditions
- Type 2 Diabetes
- Interventions
- Drug: glucagon-like peptide-1,Drug: SalineDrug: glucose dependent insulinotropic polypeptide
- First Posted Date
- 2008-02-12
- Last Posted Date
- 2008-02-12
- Lead Sponsor
- Hvidovre University Hospital
- Target Recruit Count
- 8
- Registration Number
- NCT00612950
- Locations
- 🇩🇰
Dept. of Endocrinology, Hvidovre Hospital, Copenhagen, Denmark
Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms
- Conditions
- Nicotine DependenceMajor Depressive DisorderDepression
- Interventions
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2018-10-16
- Lead Sponsor
- Butler Hospital
- Target Recruit Count
- 206
- Registration Number
- NCT00578669
- Locations
- 🇺🇸
Butler Hospital, Providence, Rhode Island, United States
Continuous Infusion of Fentanyl in Preterm on MV
- Conditions
- PainInfant, Premature, DiseasesRespiration; Insufficient or Poor, Newborn
- Interventions
- Drug: 5% glucose solution
- First Posted Date
- 2007-12-12
- Last Posted Date
- 2011-10-12
- Target Recruit Count
- 128
- Registration Number
- NCT00571636
- Locations
- 🇮🇹
St'Orsola-Malpighi General Hospital, Bologna, BO, Italy
Antioxidation Medication for Noise-induced Hearing Loss
- First Posted Date
- 2007-11-02
- Last Posted Date
- 2010-07-27
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 53
- Registration Number
- NCT00552786
- Locations
- 🇨🇳
Environmental and Occupational Medicine, National Taiwan University Hospital, Taipei, Taiwan
Influence of N-Acetylcysteine on Morbidity, Oxygenation and Cytokine Levels in Partial or Total Esophagectomy for Cancer
- Conditions
- Pulmonary Morbidity
- Interventions
- Drug: 250mL glucose 5%
- First Posted Date
- 2007-08-07
- Last Posted Date
- 2013-08-28
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 29
- Registration Number
- NCT00512265
- Locations
- 🇨🇭
University Hospital Basel, Basel, Switzerland
🇨🇭Department of Surgery, Triemli Hospital, Zurich, Switzerland, Zurich, Switzerland
Effect of Elevated Plasma-Free-Fatty-Acids on Renal Hemodynamic Parameters
- Conditions
- Renal CirculationRenal Plasma FlowGlomerular Filtration RateFatty Acids, Nonesterified
- First Posted Date
- 2007-02-06
- Last Posted Date
- 2007-02-06
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 9
- Registration Number
- NCT00431665
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Intensified Multifactorial Intervention in Patients With Type 2 Diabetes and Microalbuminuria
- Conditions
- Type 2 Diabetes
- Interventions
- Behavioral: DietBehavioral: ExerciseBehavioral: Stop smokingDrug: Glucose lowering therapyDrug: Blood pressure lowering therapyDrug: Lipid lowering therapy
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2019-04-04
- Lead Sponsor
- Peter Gæde
- Target Recruit Count
- 160
- Registration Number
- NCT00320008
- Locations
- 🇩🇰
Slagelse Hospital, Slagelse, Denmark
Glutamine and Intestinal Protein Metabolism
- Conditions
- Healthy Volunteers
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2013-06-18
- Lead Sponsor
- University Hospital, Rouen
- Target Recruit Count
- 30
- Registration Number
- NCT00213551
- Locations
- 🇫🇷
University Hospital of Rouen, Rouen, France
Drug Development Updates
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