Ivermectin
- Generic Name
- Ivermectin
- Brand Names
- Sklice, Soolantra, Stromectol
- Drug Type
- Small Molecule
- Chemical Formula
- C95H146O28
- CAS Number
- 70288-86-7
- Unique Ingredient Identifier
- 8883YP2R6D
- Background
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A (22,23-dihydroavermectin B) and 10%...
- Indication
Administered topically, ivermectin cream is indicated for the treatment of inflammatory lesions associated with rosacea. An over-the-counter ivermection lotion is commercially available and indicated for the topical treatment of head lice infestations in patients ≥6 months of age.
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- Associated Conditions
- Ascariasis, Demodex Infestation, Enterobiasis, Filariasis caused by Loa Loa, Gnathostomiasis, Head Lice Infestation, Malaria, Myiasis, Onchocerciasis caused by Infection with Onchocerca volvulus, Rosacea, Scabies, Strongyloidiasis caused by Strongyloides Stercoralis Infection, Trichuriasis
- Associated Therapies
- -
Oral Ivermectin for Chikungunya Viral Infection
- First Posted Date
- 2024-02-14
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- Prince of Songkla University
- Target Recruit Count
- 120
- Registration Number
- NCT06259383
- Locations
- 🇹🇭
Prince of Songkla University, Hat Yai, Songkhla, Thailand
Ivermectin to Prevent SARS-CoV-2 (COVID-19) Hospitalisation in Subjects Over 50
- First Posted Date
- 2023-08-15
- Last Posted Date
- 2023-08-15
- Lead Sponsor
- Insud Pharma
- Target Recruit Count
- 249
- Registration Number
- NCT05993143
- Locations
- 🇪🇸
HM Puerta del Sur, Móstoles, Madrid, Spain
🇪🇸Complejo Asistencial Universitario de Salamanca, Salamanca, Spain
🇪🇸Hospital San Pedro, Logroño, La Rioja, Spain
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm D (Ivermectin 600)
- First Posted Date
- 2023-06-08
- Last Posted Date
- 2023-11-03
- Lead Sponsor
- Susanna Naggie, MD
- Target Recruit Count
- 1459
- Registration Number
- NCT05894538
- Locations
- 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸Jadestone Clinical Research, LLC, Rockville, Maryland, United States
🇺🇸UF Health Precision Health Research, The Villages, Florida, United States
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm A (Ivermectin 400)
- First Posted Date
- 2023-02-21
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Susanna Naggie, MD
- Target Recruit Count
- 1800
- Registration Number
- NCT05736861
- Locations
- 🇺🇸
Temple University Hospital, Philadelphia, Pennsylvania, United States
🇺🇸University of Texas Health Science Center at Houston, Houston, Texas, United States
🇺🇸Sunshine Walk In Clinic, Lake Mary, Florida, United States
Comparison of Oral Ivermectin and Permethrin 5% Lotion in Treatment of Pediculosis Capitis
- Conditions
- Interventions
- First Posted Date
- 2022-12-09
- Last Posted Date
- 2022-12-09
- Lead Sponsor
- Combined Military Hospital Abbottabad
- Target Recruit Count
- 60
- Registration Number
- NCT05643820
- Locations
- 🇵🇰
CMH, Abbottabad, KPK, Pakistan
Ivermectin-artemisinin Combination Therapy for Eradication of Malaria
- First Posted Date
- 2022-11-04
- Last Posted Date
- 2022-11-04
- Lead Sponsor
- Makerere University
- Target Recruit Count
- 138
- Registration Number
- NCT05605925
- Locations
- 🇺🇬
ST. Paul's Health Center, Kasese, Uganda
Ivermectin and Balstilimab for the Treatment of Metastatic Triple Negative Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2022-04-08
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Yuan Yuan
- Target Recruit Count
- 41
- Registration Number
- NCT05318469
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Ivermectin for Post Exposure Prophylaxis of Covid-19
- First Posted Date
- 2022-02-09
- Last Posted Date
- 2022-10-18
- Lead Sponsor
- Clinical Research Centre, Malaysia
- Target Recruit Count
- 50
- Registration Number
- NCT05231603
- Locations
- 🇲🇾
KK Ayer Tawar, Sitiawan, Perak, Malaysia
🇲🇾KK Tanjung Malim, Slim River, Perak, Malaysia
🇲🇾KK Kangar, Kangar, Perlis, Malaysia
Emodepside Phase II Trial for Treatment of Onchocerciasis
- Conditions
- Interventions
- First Posted Date
- 2022-01-06
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- Drugs for Neglected Diseases
- Target Recruit Count
- 578
- Registration Number
- NCT05180461
- Locations
- 🇬🇭
University of Health and Allied Services School of Public Health, Hohoe, Volta Region, Ghana
🇨🇩Hôpital général de référence de Masimanimba, Masi-Manimba, Kwilu, Congo, The Democratic Republic of the
🇨🇩Centre de santé de référence de Kimpese, Kimpese, Kongo Central, Congo, The Democratic Republic of the
Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events
- First Posted Date
- 2021-10-20
- Last Posted Date
- 2022-09-29
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 41
- Registration Number
- NCT05085665
- Locations
- 🇨🇲
Centre de Recherche sur les Filarioses et autres Maladies Tropicales (CRFilMT), Yaoundé, Cameroon
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.