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Safimaltib

Generic Name
Safimaltib

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

Phase 1
Conditions
Leukemia, Myeloid, Acute
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, Non-Hodgkin
Myelodysplastic Syndromes
Neoplasms
Solid Tumor, Adult
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions
First Posted Date
2025-01-23
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
80
Registration Number
NCT06788509
Locations
🇨🇳

Chang Kung Memorial Hospital, Kaohsiung City, Taiwan

🇧🇪

Ghent University Hospital, Gent, Belgium

🇫🇷

Hopital Claude Huriez, Lille, France

and more 13 locations

A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL

Phase 1
Completed
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, Non-Hodgkin
Interventions
First Posted Date
2021-05-06
Last Posted Date
2025-04-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
45
Registration Number
NCT04876092
Locations
🇫🇷

Institut Paoli Calmettes, Marseille, France

🇫🇷

Hopital St Louis, Paris, France

🇩🇰

Rigshospitalet, Copenhagen, Denmark

and more 7 locations

A Study of JNJ-64264681 and JNJ-67856633 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

Phase 1
Completed
Conditions
Lymphoma, Non-Hodgkin
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2020-12-08
Last Posted Date
2025-04-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
75
Registration Number
NCT04657224
Locations
🇲🇩

Arensia Exploratory Medicine, Chisinau, Moldova, Republic of

🇮🇱

Hadassah Medical Center, Jerusalem, Israel

🇮🇱

Sheba Medical Center, Ramat Gan, Israel

and more 24 locations

A Study of JNJ-67856633 in Participants With Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Phase 1
Active, not recruiting
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, Non-Hodgkin
Interventions
First Posted Date
2019-04-03
Last Posted Date
2025-04-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
226
Registration Number
NCT03900598
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

🇺🇸

Weill Cornell Medicine, New York, New York, United States

and more 44 locations
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