Ergocalciferol

Generic Name: Ergocalciferol

Brand Names: Drisdol, Mvi Pediatric

Drug Type: Small Molecule

Chemical Formula: C_₂₈H_₄₄O

CAS Number: 50-14-6

Unique Ingredient Identifier: VS041H42XC

Background: Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the first time from yeast in 1931...

Indication: Ergocalciferol is indicated for the treatment of hypoparathyroidism, refractory rickets, and familial hypophosphatemia.

Hypoparathyroidism is the result of inadequate parathyroid hormone production that occurs due to the presence of damage or removal of the parathyroid glands. This condition produces decreased calcium and increased phosphorus levels.
...

Associated Conditions: Deficiency, Vitamin A, Deficiency, Vitamin D, Hypoparathyroidism, Hypophosphatemia, Familial, Vitamin D Resistant Rickets

Associated Therapies: Dietary supplementation

Clinical Trials

Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?

Phase 4

Completed

Conditions: Vitamin D Deficiency
25-Hydroxyvitamin D Concentration

Interventions: Drug: Vitamin D3
Drug: Vitamin D2
Drug: Placebo oral capsule

First Posted Date: 2017-01-27

Last Posted Date: 2018-08-13

Lead Sponsor: King Faisal Specialist Hospital & Research Center

Target Recruit Count: 100

Registration Number: NCT03035084

Locations: 🇸🇦
King Faisal Specialist Hospital & Research Center, Riyadh, Central, Saudi Arabia

Efficacy of Vitamin D Therapy on Glucose Homeostasis in Obese Adolescents

Not Applicable

Completed

Conditions: Vitamin D Deficiency

Interventions: Drug: Placebo
Drug: Vitamin D2

First Posted Date: 2015-04-10

Last Posted Date: 2017-03-17

Lead Sponsor: NYU Langone Health

Target Recruit Count: 20

Registration Number: NCT02414529

Locations: 🇺🇸
bellevue hospital CTSI, New York, New York, United States

Ergocalciferol Therapy in Calcidiol Deficient, Hemodialysis Patients on Therapeutic Doses of Paricalcitol

Phase 1

Completed

Conditions: Insulin Resistance
Inflammation

Interventions: Drug: Ergocalciferol
Drug: Placebo

First Posted Date: 2013-12-13

Last Posted Date: 2016-08-11

Lead Sponsor: University of Utah

Target Recruit Count: 58

Registration Number: NCT02011828

Locations: 🇺🇸
University of Utah, Salt Lake City, Utah, United States

Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition

Phase 4

Conditions: Vitamin D Deficiency
Malnutrition

Interventions: Drug: 1,25(OH)2 Vitamin D3
Dietary Supplement: low protein diet
Dietary Supplement: normal protein diet
Drug: Vitamin D2

First Posted Date: 2013-12-09

Last Posted Date: 2013-12-09

Lead Sponsor: Wenhu Liu

Target Recruit Count: 600

Registration Number: NCT02005302

Locations: 🇨🇳
Sino-Japanese Friendship Hospital, Beijing, Beijing, China
🇨🇳
People's Liberation Army Air Force General Hospital, Beijing, Beijing, China
🇨🇳
People's Liberation Army General Hospital, Beijing, Beijing, China

and more 2 locations

How Bone is Made in Children Receiving Dialysis

Phase 4

Conditions: Bone Mineralization Defect

Interventions: Drug: Vitamin D2

First Posted Date: 2013-02-26

Last Posted Date: 2013-02-26

Lead Sponsor: University of California, Los Angeles

Target Recruit Count: 60

Registration Number: NCT01799317

Locations: 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Loma Linda University, Loma Linda, California, United States

Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients

Not Applicable

Conditions: Chronic Kidney Disease
Vitamin D Deficiency

Interventions: Drug: Vitamin D2

First Posted Date: 2012-08-24

Last Posted Date: 2012-08-30

Lead Sponsor: Peking University People's Hospital

Target Recruit Count: 350

Registration Number: NCT01672047

Locations: 🇨🇳
The People's Hospital of Peking University, Beijing, Beijing, China

Efficacy of Vitamin D2 to Treat Chronic Kidney Disease Mineral and Bone Disorder

Phase 4

Completed

Conditions: Vitamin D Deficiency

Interventions: Drug: 1,25(OH)2 Vit D3
Drug: Vitamin D2

First Posted Date: 2012-07-04

Last Posted Date: 2016-02-15

Lead Sponsor: Dongliang Zhang, MD

Target Recruit Count: 204

Registration Number: NCT01633853

Locations: 🇨🇳
Beijing Friedship Hospital, Beijing, Beijing, China

Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease

Phase 1

Completed

Conditions: Peyronie's Disease

Interventions: Drug: Testosterone Pellets
Drug: Vitamin D2
Drug: Vitamin E

First Posted Date: 2012-04-17

Last Posted Date: 2018-03-29

Lead Sponsor: Men's Health Boston

Target Recruit Count: 75

Registration Number: NCT01578473

Locations: 🇺🇸
Men's Health Boston, Chestnut Hill, Massachusetts, United States

Vitamin D Repletion in Coronary Artery Disease

Not Applicable

Completed

Conditions: Vitamin D Deficiency
Coronary Artery Disease
Endothelial Dysfunction
Inflammation

Interventions: Drug: Ergocalciferol
Other: Sugar pill

First Posted Date: 2012-04-04

Last Posted Date: 2013-10-10

Lead Sponsor: Seth I. Sokol, M.D.

Target Recruit Count: 96

Registration Number: NCT01570309

Locations: 🇺🇸
Montefiore Medical Center / Weiler division, Bronx, New York, United States
🇺🇸
Jacobi Medical Center, Bronx, New York, United States

Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms

Phase 4

Completed

Conditions: Myopathic Symptoms

Interventions: Drug: Placebo
Drug: Ergocalciferol

First Posted Date: 2012-04-02

Last Posted Date: 2021-06-10

Lead Sponsor: Cedars-Sinai Medical Center

Target Recruit Count: 11

Registration Number: NCT01568255

Locations: 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States

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