Ipratropium
- Generic Name
- Ipratropium
- Brand Names
- Atrovent, Combivent, Ipravent
- Drug Type
- Small Molecule
- Chemical Formula
- C20H30NO3
- CAS Number
- 60205-81-4
- Unique Ingredient Identifier
- GR88G0I6UL
- Background
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.
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- Indication
Inhaled ipratropium is indicated in combination with inhaled beta-agonist systemic corticosteroids for the management of severe exacerbations of asthma flares requiring treatment.
Asthma exacerbations are characterized by a progressive increase in one or more of asthma symptoms accompanied by a decrease in expiratory flow.
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- Associated Conditions
- Acute Exacerbation of Asthma, Asthma, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD), Nasal Congestion Associated With the Common Cold, Non-Allergic Rhinitis, Perennial Allergic Rhinitis (PAR), Rhinitis
- Associated Therapies
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Budesonide Inhalation Suspension for Acute Asthma in Children
- First Posted Date
- 2006-10-27
- Last Posted Date
- 2012-08-10
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 179
- Registration Number
- NCT00393367
- Locations
- 🇺🇸
Children's Hospital of Philadelphia Emergency Department, Philadelphia, Pennsylvania, United States
Effect of Ipratropium on Acute Bronchitis in Subjects Without Underlying Lung Disease
- Conditions
- First Posted Date
- 2006-09-04
- Last Posted Date
- 2008-10-17
- Lead Sponsor
- Kaiser Permanente
- Target Recruit Count
- 200
- Registration Number
- NCT00371527
- Locations
- 🇺🇸
South Sacramento Kaiser Permanente, Sacramento, California, United States
Comparison of Tiotropium and Ipratropium in a Double-Blind, Double-dummy, Efficacy and Safety Study in Adults With COPD
- Conditions
- First Posted Date
- 2006-01-10
- Last Posted Date
- 2013-11-01
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 141
- Registration Number
- NCT00274040
- Locations
- 🇰🇷
Chung-ang University Hospital, Seoul, Korea, Republic of
🇰🇷Kangnam St. Mary's Hospital, Seoul, Korea, Republic of
🇰🇷Jeonnam National University Hospital, Kwangju, Korea, Republic of
Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2011-04-19
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 32
- Registration Number
- NCT00202176
- Locations
- 🇨🇦
Respiratory Investigation Unit, Kingston, Ontario, Canada
Lung Health Study (LHS) I and III
- Conditions
Drug Development Updates
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