Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain).
Investigated for use/treatment in interstitial cystitis and urinary incontinence.
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
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