Dexibuprofen
- Generic Name
- Dexibuprofen
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 51146-56-6
- Unique Ingredient Identifier
- 671DKG7P5S
- Background
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability . For Metabolism, Enzymes, Carriers, Transporters Sections, refer to Ibuprofen.
- Indication
For more information, refer to ibuprofen.
- Associated Conditions
- Fever, Inflammation, Pain, Spasms
- Associated Therapies
- Analgesia
Phase I Study to Evaluate the Safety of Dexibuprofen 300mg Under Fasting and Fed Conditions
- First Posted Date
- 2016-11-06
- Last Posted Date
- 2020-11-18
- Lead Sponsor
- Apsen Farmaceutica S.A.
- Target Recruit Count
- 52
- Registration Number
- NCT02956512
- Locations
- 🇧🇷
Azidus laboratories Ltd., Valinhos, São Paulo, Brazil
Phase I Study to Evaluate the Safety of Dexibuprofen 200mg Under Fasting and Fed Conditions
- First Posted Date
- 2016-11-06
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Apsen Farmaceutica S.A.
- Target Recruit Count
- 52
- Registration Number
- NCT02956525
- Locations
- 🇧🇷
Azidus laboratories Ltd., Valinhos, São Paulo, Brazil
Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee
- Conditions
- Interventions
- First Posted Date
- 2010-02-10
- Last Posted Date
- 2012-07-10
- Lead Sponsor
- Gebro Pharma GmbH
- Target Recruit Count
- 482
- Registration Number
- NCT01066676
- Locations
- 🇦🇹
Rheuma Zentrum Favoriten, Vienna, Austria
🇦🇹Rehabzentrum für Erkrankungen des rheumat. Formenkreises, Bad Hofgastein, Salzburg, Austria
The Efficacy and Safety of Dexibuprofen Syrup
- Conditions
- Interventions
- First Posted Date
- 2008-12-22
- Last Posted Date
- 2010-01-18
- Lead Sponsor
- Inje University
- Target Recruit Count
- 260
- Registration Number
- NCT00812422
- Locations
- 🇰🇷
Inje University Sanggye Paik Hospital, Seoul, Korea, Republic of
🇰🇷Asan Medical Center, Seoul, Korea, Republic of
🇰🇷Kyung Hee University Hospital, Seoul, Korea, Republic of
Drug Development Updates
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