MedPath

Oral Polio Vaccine

Generic Name
Oral Polio Vaccine
Drug Type
Biotech

Overview

The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. Strains of the virus are selected based on their reduced incidence of spreading to the central nervous system but still having the ability to mimic the immune response that occurs after infection with the wild poliovirus. The vaccine is created by weakening the wildtype before being placed into the oral vaccine. After administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population. With administration, this vaccine prevents cases of paralytic poliomyelitis. The polio vaccine can be either administered in the inactivated form or the oral form, although both series comprises 4 doses and is also interchangeable in administration form so long all as 4 doses are completed.

Background

The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. Strains of the virus are selected based on their reduced incidence of spreading to the central nervous system but still having the ability to mimic the immune response that occurs after infection with the wild poliovirus. The vaccine is created by weakening the wildtype before being placed into the oral vaccine. After administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population. With administration, this vaccine prevents cases of paralytic poliomyelitis. The polio vaccine can be either administered in the inactivated form or the oral form, although both series comprises 4 doses and is also interchangeable in administration form so long all as 4 doses are completed.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

Clinical Trials

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Posted
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No clinical trials found

No clinical trials found for this drug

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code

No FDA products found

No FDA products found for this drug

EMA Approved Products

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EMA Number
Auth. Holder
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Status
Issued
Opinion
Revision

No EMA products found

No EMA products found for this drug

Singapore Approved Products

Product Name
Manufacturer
Dosage Form
Strength
Approved
Approval No.
Online
INFANRIX IPV+HIB VACCINE
GlaxoSmithKline Biologicals, GlaxoSmithKline Biologicals SA
INJECTION
8DU/0.5ml
1999/06/25
SIN10988P
Yes
INFANRIX IPV+HIB VACCINE
GlaxoSmithKline Biologicals, GlaxoSmithKline Biologicals SA
INJECTION
32DU/0.5ml
1999/06/25
SIN10988P
Yes
INFANRIX IPV+HIB VACCINE
GlaxoSmithKline Biologicals, GlaxoSmithKline Biologicals SA
INJECTION
40DU/0.5ml
1999/06/25
SIN10988P
Yes

China Approved Products

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Approval No.
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Type
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Import

No China products found

No China products found for this drug

Australia Approved Products

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ARTG ID
Sponsor
Status
Reg. Date
Ingredient

No Australia products found

No Australia products found for this drug

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