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HSA Approval

INFANRIX IPV+HIB VACCINE

SIN10988P

INFANRIX IPV+HIB VACCINE

INFANRIX IPV+HIB VACCINE

June 25, 1999

GLAXOSMITHKLINE PTE LTD

GLAXOSMITHKLINE PTE LTD

Regulatory Information

GLAXOSMITHKLINE PTE LTD

GLAXOSMITHKLINE PTE LTD

Therapeutic

Prescription Only

Formulation Information

INJECTION

**Dosage and Administration** **Posology** The primary vaccination schedule consists of three doses in the first 6 months of life and can start from the age of 2 months. An interval of at least 1 month should be maintained between subsequent doses. A booster dose is recommended in the second year of life, with an interval of at least 6 months after completion of primary vaccination schedule. **Method of administration** _**Infanrix-IPV+Hib**_ is for **deep** intramuscular injection, in the anterolateral thigh. It is preferable that each subsequent dose is given at alternate sites. _**Infanrix-IPV+Hib**_ should be administered with caution to subjects with thrombocytopenia or a bleeding disorder since bleeding may occur following an intramuscular administration to these subjects. Firm pressure should be applied to the injection site (without rubbing) for at least two minutes.

INTRAMUSCULAR

Medical Information

**Indications** _**Infanrix-IPV+Hib**_ is indicated for active immunisation in infants from the age of 2 months against diphtheria, tetanus, pertussis, poliomyelitis and _Haemophilus influenzae_ type b. _**Infanrix-IPV+Hib**_ is also indicated as a booster dose for children who have previously been immunised with diphtheria, tetanus, pertussis (DTP), polio and Hib antigens. _**Infanrix-IPV+Hib**_ does not protect against diseases caused by other types of _Haemophilus influenzae_ nor against meningitis caused by other organisms.

**Contraindications** _**Infanrix-IPV+Hib**_ should not be administered to subjects with known hypersensitivity to any component of the vaccine, or to subjects having shown signs of hypersensitivity after previous administration of diphtheria, tetanus, pertussis, inactivated polio or Hib vaccines. _**Infanrix-IPV+Hib**_ is contraindicated if the child has experienced an encephalopathy of unknown aetiology, occurring within 7 days following previous vaccination with pertussis-containing vaccine.

J07CA06

diphtheria-haemophilus influenzae B-pertussis-poliomyelitis-tetanus

Manufacturer Information

GLAXOSMITHKLINE PTE LTD

GlaxoSmithKline Biologicals

GlaxoSmithKline Biologicals SA

Active Ingredients

DIPHTHERIA TOXOID (D)

min 30IU/0.5ml

TETANUS TOXOID (T)

min 40IU/0.5ml

PERTUSSIS TOXOID (PT)

25mcg/0.5ml

FILAMENTOUS HAEMAGGLUTININ (FHA)

25mcg/0.5ml

HIB PURIFIED CAPSULAR POLYSACCHARIDE

10 mcg/0.5 ml

POLIO VIRUS TYPE 2 (INACTIVATED)

8DU/0.5ml

Oral Polio Vaccine

PERTACTIN (PRN or 69kDa Outer Membrane Protein)

8mcg/0.5ml

POLIO VIRUS TYPE 3 (INACTIVATED)

32DU/0.5ml

Oral Polio Vaccine

POLIO VIRUS TYPE 1 (INACTIVATED)

40DU/0.5ml

Oral Polio Vaccine

Documents

Package Inserts

Infanrix-IPV+Hib PI.pdf

Approved: May 31, 2023

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