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Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins

Generic Name
Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins
Drug Type
Biotech
Unique Ingredient Identifier
3ME9TTI5QB
Background

Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. Lipoaspiration, also known as liposuction, is a possible method for extraction. This is followed by purification and expansion of the cells in vitro.

These AMSCs are multipotent, with the capability of forming different tissues, some of which include bone, muscle, neural, and chondrocyte. This explains why AMSCs have been utilized in repairing craniofacial bone defects. They also have potential in treatment of scarred vocal folds.

Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease

Phase 2
Not yet recruiting
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2020-07-22
Last Posted Date
2022-09-28
Lead Sponsor
Nature Cell Co. Ltd.
Target Recruit Count
100
Registration Number
NCT04482413

Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.

Phase 2
Recruiting
Conditions
Systemic Sclerosis
Interventions
Drug: Placebo
First Posted Date
2020-04-22
Last Posted Date
2023-11-13
Lead Sponsor
University Hospital, Toulouse
Target Recruit Count
32
Registration Number
NCT04356755
Locations
🇫🇷

Grenoble Hospital, Grenoble, France

🇫🇷

Lille Hopsital, Lille, France

🇫🇷

Marseille Hospital, Marseille, France

and more 4 locations

Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome

Phase 1
Completed
Conditions
Acute Respiratory Distress Syndrome
Interventions
First Posted Date
2020-02-28
Last Posted Date
2024-02-28
Lead Sponsor
Histocell, S.L.
Target Recruit Count
26
Registration Number
NCT04289194
Locations
🇪🇸

Hospital Universitario de Cruces, Barakaldo, Bizkaia, Spain

🇪🇸

Fundación Jiménez Díaz, Madrid, Spain

A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy

Phase 1
Completed
Conditions
Traumatic Brain Injury
Interventions
First Posted Date
2019-08-21
Last Posted Date
2025-01-27
Lead Sponsor
Hope Biosciences
Target Recruit Count
24
Registration Number
NCT04063215
Locations
🇺🇸

Memorial Hermann Hospital-Clinical Research Unit (MMH-CRU), Houston, Texas, United States

A Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Other: Placebo-Control
First Posted Date
2017-04-18
Last Posted Date
2021-08-10
Lead Sponsor
Nature Cell Co. Ltd.
Target Recruit Count
21
Registration Number
NCT03117738
Locations
🇺🇸

ATP Clinical Research, Costa Mesa, California, United States

🇺🇸

Syrentis Clinical Research, Santa Ana, California, United States

🇺🇸

Valden Medical, Honolulu, Hawaii, United States

Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury

Phase 1
Completed
Conditions
Spinal Cord Injury
First Posted Date
2012-06-21
Last Posted Date
2015-02-13
Lead Sponsor
Bukwang Pharmaceutical
Target Recruit Count
15
Registration Number
NCT01624779
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Seongbukgu, Korea, Republic of

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