Allopurinol
- Generic Name
- Allopurinol
- Brand Names
- Aloprim, Zyloprim
- Drug Type
- Small Molecule
- Chemical Formula
- C5H4N4O
- CAS Number
- 315-30-0
- Unique Ingredient Identifier
- 63CZ7GJN5I
- Background
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
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- Indication
Allopurinol is indicated in :
1) the management of patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy).
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- Associated Conditions
- Hyperuricemia, Primary Gout, Recurrent calcium oxalate calculi, Secondary gout, Calcium oxalate calculi Renal Calculi
- Associated Therapies
- -
Allopurinol in Acute Coronary Syndrome
- First Posted Date
- 2011-10-24
- Last Posted Date
- 2015-05-27
- Lead Sponsor
- Stephen McSwiggan
- Target Recruit Count
- 26
- Registration Number
- NCT01457820
- Locations
- 🇬🇧
NHS Tayside, Dundee, Angus, United Kingdom
Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol
- Conditions
- Interventions
- First Posted Date
- 2011-10-14
- Last Posted Date
- 2014-05-12
- Lead Sponsor
- Regeneron Pharmaceuticals
- Target Recruit Count
- 82
- Registration Number
- NCT01451645
Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients
- Conditions
- Interventions
- First Posted Date
- 2011-07-21
- Last Posted Date
- 2015-09-18
- Lead Sponsor
- CymaBay Therapeutics, Inc.
- Target Recruit Count
- 100
- Registration Number
- NCT01399008
Allopurinol Outcome Study
- First Posted Date
- 2011-07-12
- Last Posted Date
- 2014-06-17
- Lead Sponsor
- Ardea Biosciences, Inc.
- Target Recruit Count
- 1735
- Registration Number
- NCT01391325
Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function
- Conditions
- Interventions
- First Posted Date
- 2011-03-22
- Last Posted Date
- 2017-06-29
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 242
- Registration Number
- NCT01320722
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gout
- First Posted Date
- 2011-03-08
- Last Posted Date
- 2011-03-08
- Target Recruit Count
- 57
- Registration Number
- NCT01310673
- Locations
- 🇺🇸
White River Junction VA Medical Center, White River Junction, Vermont, United States
Uric Acid and the Endothelium in CKD
- First Posted Date
- 2010-10-27
- Last Posted Date
- 2017-06-28
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 80
- Registration Number
- NCT01228903
- Locations
- 🇺🇸
University of Colorado at Denver, Aurora, Colorado, United States
Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2
- First Posted Date
- 2010-09-13
- Last Posted Date
- 2020-01-31
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 55
- Registration Number
- NCT01200485
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Hyperuricemia on Hypertension and Metabolic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2010-07-08
- Last Posted Date
- 2014-07-24
- Lead Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
- Target Recruit Count
- 40
- Registration Number
- NCT01157936
- Locations
- 🇲🇽
Insituto Nacional de Cardiología Ignacio Chávez, Mexico, Mexico
Allopurinol as a Possible Oxygen Sparing Agent During Exercise in Peripheral Arterial Disease
- First Posted Date
- 2010-06-22
- Last Posted Date
- 2017-05-02
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 50
- Registration Number
- NCT01147705
- Locations
- 🇬🇧
Ninewells Hospital, Dundee, United Kingdom
Drug Development Updates
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