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Oxazepam

Generic Name
Oxazepam
Brand Names
Oxpam
Drug Type
Small Molecule
Chemical Formula
C15H11ClN2O2
CAS Number
604-75-1
Unique Ingredient Identifier
6GOW6DWN2A

Overview

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism. It is an active metabolite of both diazepam and temazepam and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions.

Background

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism. It is an active metabolite of both diazepam and temazepam and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions.

Indication

Oxazepam is indicated for the management of anxiety disorders and for the short-term relief of symptoms of anxiety. It may also be used in the management of alcohol withdrawal symptoms.

Associated Conditions

  • Alcohol Withdrawal Syndrome
  • Anxiety
  • Anxiety Disorders

FDA Approved Products

Oxazepam
Manufacturer:TruPharma, LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2021/03/03
NDC:52817-290
Oxazepam
Manufacturer:American Health Packaging
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/12/02
NDC:62584-812
Oxazepam
Manufacturer:American Health Packaging
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/12/02
NDC:62584-813
OXAZEPAM
Manufacturer:STAT RX USA LLC
Route:ORAL
Strength:15 mg in 1 1
Approved: 2009/12/15
NDC:16590-304
Oxazepam
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2014/03/31
NDC:67544-117

Singapore Approved Products

No Singapore products found for this drug

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