Bafetinib
- Generic Name
- Bafetinib
- Drug Type
- Small Molecule
- Chemical Formula
- C30H31F3N8O
- CAS Number
- 859212-16-1
- Unique Ingredient Identifier
- NVW4Z03I9B
- Background
Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases
Phase 1
Completed
- Conditions
- Adult Anaplastic AstrocytomaAdult Giant Cell GlioblastomaAdult GliosarcomaAdult Anaplastic EpendymomaAdult Anaplastic OligodendrogliomaAdult GlioblastomaAdult Mixed GliomaRecurrent Adult Brain TumorTumors Metastatic to BrainAdult Anaplastic Oligoastrocytoma
- Interventions
- Procedure: microdialysisOther: pharmacological studyOther: liquid chromatographyOther: mass spectrometryOther: laboratory biomarker analysisGenetic: protein expression analysisGenetic: western blottingOther: immunohistochemistry staining methodProcedure: therapeutic conventional surgery
- First Posted Date
- 2010-11-04
- Last Posted Date
- 2018-04-17
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 7
- Registration Number
- NCT01234740
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
🇺🇸South Pasadena Cancer Center, South Pasadena, California, United States
Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate Cancer
- First Posted Date
- 2010-10-07
- Last Posted Date
- 2011-12-15
- Lead Sponsor
- CytRx
- Target Recruit Count
- 23
- Registration Number
- NCT01215799
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
Study of Bafetinib as Treatment for Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL)
- First Posted Date
- 2010-06-15
- Last Posted Date
- 2013-05-15
- Lead Sponsor
- CytRx
- Target Recruit Count
- 20
- Registration Number
- NCT01144260
- Locations
- 🇺🇸
UT M.D. Anderson Cancer Center, Houston, Texas, United States
🇺🇸City of Hope National Medical Center, Duarte, California, United States
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