Bosentan
- Generic Name
- Bosentan
- Brand Names
- Stayveer, Tracleer
- Drug Type
- Small Molecule
- Chemical Formula
- C27H29N5O6S
- CAS Number
- 147536-97-8
- Unique Ingredient Identifier
- XUL93R30K2
Overview
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Background
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Indication
Used in the treatment of pulmonary arterial hypertension (PAH), to improve exercise ability and to decrease the rate of clinical worsening (in patients with WHO Class III or IV symptoms).
Associated Conditions
- NYHA Functional Class II-IV Pulmonary arterial hypertension
- Ocular Inflammation
- Ocular bacterial infections
Clinical Trials
FDA Approved Products
Singapore Approved Products
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