Etacrynic acid
- Generic Name
- Etacrynic acid
- Brand Names
- Edecrin
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12Cl2O4
- CAS Number
- 58-54-8
- Unique Ingredient Identifier
- M5DP350VZV
- Background
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
- Indication
For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.
- Associated Conditions
- Ascites, Congenital Heart Disease (CHD), Edema, Nephrotic Syndrome
- Associated Therapies
- -
Ethacrynic Acid Elimination in Non-Muscle Invasive Bladder Cancer Patients Undergoing Transurethral Resection
- First Posted Date
- 2016-08-02
- Last Posted Date
- 2017-08-22
- Lead Sponsor
- Eugene Lee, MD
- Target Recruit Count
- 12
- Registration Number
- NCT02852564
- Locations
- 🇺🇸
The University of Kansas Medical Center, Kansas City, Kansas, United States
Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease
- First Posted Date
- 2012-06-27
- Last Posted Date
- 2014-07-24
- Lead Sponsor
- Bambino Gesù Hospital and Research Institute
- Target Recruit Count
- 74
- Registration Number
- NCT01628731
- Locations
- 🇮🇹
Bambino Gesù Hospital, Rome, Italy
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