Levocarnitine
- Generic Name
- Levocarnitine
- Brand Names
- Carnitor
- Drug Type
- Small Molecule
- Chemical Formula
- C7H15NO3
- CAS Number
- 541-15-1
- Unique Ingredient Identifier
- 0G389FZZ9M
- Background
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
- Indication
⑴用于继发性肉碱缺乏症。主要用于慢性肾衰长期血透患者因肉碱缺乏产生的一系列并发症状，临床表现如心肌病、骨骼肌病、心律失常、高脂血症，以及低血压和透析中肌痉挛等。
⑵用于罕见病β-酮硫解酶缺乏症（BKD）和原发性肉碱缺乏症（PCD）。
⑶用于罕见病戊二酸Ⅰ型。
⑷用于维持罕见病同型半胱氨酸血症引起的血液游离肉碱的正常水平。
- Associated Conditions
- Carnitine Deficiency, Congenital carnitine deficiency, Secondary Carnitine deficiency
- Associated Therapies
- -
Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI
- Conditions
- Interventions
- First Posted Date
- 2024-08-21
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 76
- Registration Number
- NCT06564909
Carnitine Supplementation in Pediatric Hemodialysis Patients
- Conditions
- Interventions
- First Posted Date
- 2023-07-17
- Last Posted Date
- 2023-07-17
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 40
- Registration Number
- NCT05948124
- Locations
- 🇪🇬
Ain Shams university, Cairo, Egypt
L-carnitine in Modulating Pain and Inflammation in Rheumatoid Arthritis
- First Posted Date
- 2023-03-31
- Last Posted Date
- 2023-03-31
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 46
- Registration Number
- NCT05792527
- Locations
- 🇪🇬
Tanta university, Tanta, Gharbia, Egypt
Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia
- Conditions
- Interventions
- First Posted Date
- 2022-08-16
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- Children's Hospital of Orange County
- Target Recruit Count
- 20
- Registration Number
- NCT05501899
- Locations
- 🇺🇸
Children's Hospital of Orange County, Orange, California, United States
🇺🇸Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California, United States
A Randomized Controlled Trial to Assess the Effect of L-carnitine in Patients With Diabetic Peripheral Neuropathy to Relief Pain and Symptom Improvement
- First Posted Date
- 2019-10-30
- Last Posted Date
- 2019-10-30
- Target Recruit Count
- 104
- Registration Number
- NCT04145245
- Locations
- 🇧🇩
Pharmacology department,BSMMU., Dhaka, Dhaka,Sahbagh, Bangladesh
L-Carnitine as an Adjuvant Treatment in Acute Phosphide Poisoning (LC)
- First Posted Date
- 2019-05-16
- Last Posted Date
- 2019-05-16
- Lead Sponsor
- Heba Allah Ali Abd El-Halim Mabrouk
- Target Recruit Count
- 50
- Registration Number
- NCT03953248
Levocarnitine for Dry Eye in Sjogren's Syndrome
- Conditions
- Interventions
- First Posted Date
- 2019-05-16
- Last Posted Date
- 2024-03-08
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 15
- Registration Number
- NCT03953703
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective Drugs
- Conditions
- Interventions
- First Posted Date
- 2018-09-06
- Last Posted Date
- 2019-06-17
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 150
- Registration Number
- NCT03660293
- Locations
- 🇪🇬
Faculty of Medicine- Tanta University, Tanta, Gharbia, Egypt
Adding L-Carnitine to Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
- Conditions
- Interventions
- First Posted Date
- 2018-08-14
- Last Posted Date
- 2018-08-14
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 150
- Registration Number
- NCT03630341
Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver
- Conditions
- Interventions
- First Posted Date
- 2018-07-27
- Last Posted Date
- 2018-08-23
- Lead Sponsor
- IlDong Pharmaceutical Co Ltd
- Target Recruit Count
- 76
- Registration Number
- NCT03604016
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.