Levocarnitine
- Generic Name
- Levocarnitine
- Brand Names
- Carnitor
- Drug Type
- Small Molecule
- Chemical Formula
- C7H15NO3
- CAS Number
- 541-15-1
- Unique Ingredient Identifier
- 0G389FZZ9M
- Background
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
- Indication
⑴用于继发性肉碱缺乏症。主要用于慢性肾衰长期血透患者因肉碱缺乏产生的一系列并发症状，临床表现如心肌病、骨骼肌病、心律失常、高脂血症，以及低血压和透析中肌痉挛等。
⑵用于罕见病β-酮硫解酶缺乏症（BKD）和原发性肉碱缺乏症（PCD）。
⑶用于罕见病戊二酸Ⅰ型。
⑷用于维持罕见病同型半胱氨酸血症引起的血液游离肉碱的正常水平。
- Associated Conditions
- Carnitine Deficiency, Congenital carnitine deficiency, Secondary Carnitine deficiency
Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis
- First Posted Date
- 2025-05-07
- Last Posted Date
- 2025-05-07
- Lead Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
- Target Recruit Count
- 72
- Registration Number
- NCT06960694
- Locations
- 🇧🇩
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Dhaka, Bangladesh
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
- First Posted Date
- 2025-03-28
- Last Posted Date
- 2025-04-04
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 176
- Registration Number
- NCT06901323
- Locations
- 🇪🇬
Mansoura University, Mansoura, Egypt
L-carnitine Supplementation in Rheumatoid Arthritis Patients
- Conditions
- Rheumatoid Arthritis (RA)
- Interventions
- Drug: Disease-modifying anti-rheumatic drugs
- First Posted Date
- 2024-12-31
- Last Posted Date
- 2025-01-07
- Lead Sponsor
- German University in Cairo
- Target Recruit Count
- 60
- Registration Number
- NCT06753565
- Locations
- 🇪🇬
Demerdash hospital, Cairo, Demerdash, Egypt
Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI
- Conditions
- Reperfusion Injury, MyocardialMyocardial Infarction
- Interventions
- Drug: The standard care for the management of myocardial infarction post PCI
- First Posted Date
- 2024-08-21
- Last Posted Date
- 2025-01-28
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 76
- Registration Number
- NCT06564909
Carnitine Supplementation in Pediatric Hemodialysis Patients
- Conditions
- Carnitine Deficiency Due to Hemodialysis
- Interventions
- Other: isotonic saline
- First Posted Date
- 2023-07-17
- Last Posted Date
- 2023-07-17
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 40
- Registration Number
- NCT05948124
- Locations
- 🇪🇬
Ain Shams university, Cairo, Egypt
Impact of Hemodialysis on Plasma Carnitine Levels in Patients With End Stage Renal Disease
- Conditions
- Hemodialysis Complication
- Interventions
- First Posted Date
- 2023-04-18
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- Bahria University
- Target Recruit Count
- 83
- Registration Number
- NCT05817799
- Locations
- 🇵🇰
Jinnah Post Graduate Medical Center, Karachi, Sindh, Pakistan
L-carnitine in Modulating Pain and Inflammation in Rheumatoid Arthritis
- First Posted Date
- 2023-03-31
- Last Posted Date
- 2023-03-31
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 46
- Registration Number
- NCT05792527
- Locations
- 🇪🇬
Tanta university, Tanta, Gharbia, Egypt
Effects of L-carnitine Therapy on the Heart of Maintenance Hemodialysis Patients
- First Posted Date
- 2023-01-06
- Last Posted Date
- 2024-08-06
- Lead Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
- Target Recruit Count
- 1008
- Registration Number
- NCT05673239
- Locations
- 🇨🇳
The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children With Moderate Persistent Asthma
- Conditions
- Moderate Persistent Asthma
- Interventions
- First Posted Date
- 2022-11-30
- Last Posted Date
- 2022-11-30
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 66
- Registration Number
- NCT05632549
- Locations
- 🇪🇬
Tanta University Hospital, Tanta, Gharbia, Egypt
Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia
- Conditions
- Acute Lymphoblastic LeukemiaHepatotoxicity
- Interventions
- First Posted Date
- 2022-08-16
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- Children's Hospital of Orange County
- Target Recruit Count
- 20
- Registration Number
- NCT05501899
- Locations
- 🇺🇸
Children's Hospital of Orange County, Orange, California, United States
🇺🇸Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California, United States
Drug Development Updates
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