Urea
- Generic Name
- Urea
- Brand Names
- Cem-urea, Umecta, Utopic
- Drug Type
- Small Molecule
- Chemical Formula
- CH4N2O
- CAS Number
- 57-13-6
- Unique Ingredient Identifier
- 8W8T17847W
- Background
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
- Indication
Urea is used topically for debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma, corns and calluses, as well as damaged, devitalized and ingrown nails.
- Associated Conditions
- Allergic Skin Reaction, Atopic Dermatitis, Contact Dermatitis, Dermatitis, Dry Eyes, Dry Skin, Dry Skin; Eczema, Eczema, Dyshidrotic, Eye pruritus, Helicobacter Pylori Infection, Insect Bites, Lichen Planus (LP), Neurodermatitis, Nummular Dermatitis, Psoriasis, Seborrheic Dermatitis, Sunburn, Anal eczema, Calluses
- Associated Therapies
- Moisturizing
Urea for Chronic Hyponatremia
- First Posted Date
- 2020-10-19
- Last Posted Date
- 2024-05-20
- Lead Sponsor
- Helbert Rondon Berrios, MD, MS
- Target Recruit Count
- 2
- Registration Number
- NCT04588207
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage
- Conditions
- HyponatremiaSubarachnoid HemorrhageSIADH
- Interventions
- Other: PLACEBODrug: Urea
- First Posted Date
- 2020-09-17
- Last Posted Date
- 2023-12-11
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 52
- Registration Number
- NCT04552873
- Locations
- 🇫🇷
University Hospital Grenoble, Grenoble, France
Comparison of 12% Ammonium Lactate and 10% Urea Cream in Geriatric With Xerosis Cutis
- First Posted Date
- 2019-10-15
- Last Posted Date
- 2019-10-15
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 40
- Registration Number
- NCT04127513
- Locations
- 🇮🇩
Faculty of Medicine University of Indonesia, Jakarta Pusat, DKI Jakarta, Indonesia
A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema
- First Posted Date
- 2007-12-19
- Last Posted Date
- 2008-10-13
- Lead Sponsor
- ACO Hud Nordic AB
- Target Recruit Count
- 53
- Registration Number
- NCT00576550
- Locations
- 🇳🇴
Medi 3 Innlandet, Hamar, Norway
🇳🇴Colosseumklinikken, Oslo, Norway
🇳🇴Dr Funks hudklinikk, Oslo, Norway
Skin Tolerance Study of Betamethasone Creams in Atopic Eczema and the Preventative Properties of a Moisturiser
- First Posted Date
- 2007-12-19
- Last Posted Date
- 2008-10-13
- Lead Sponsor
- ACO Hud Nordic AB
- Target Recruit Count
- 55
- Registration Number
- NCT00576238
- Locations
- 🇸🇪
Nacka hudmottagning, Nacka, Sweden
🇸🇪Sophiahemmet, Stockholm, Sweden
🇸🇪Läkarhuset Vällingby, Vällingby, Sweden
Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion
- Conditions
- Infant, Low Birth WeightHyperglycemia
- First Posted Date
- 2000-06-05
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 96
- Registration Number
- NCT00005889
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
Drug Development Updates
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