Norelgestromin
- Generic Name
- Norelgestromin
- Brand Names
- Evra, Xulane, Zafemy
- Drug Type
- Small Molecule
- Chemical Formula
- C21H29NO2
- CAS Number
- 53016-31-2
- Unique Ingredient Identifier
- R0TAY3X631
- Background
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
- Indication
Norelgestromin is used for contraception and menopausal hormonal therapy. Norelgestromin may potentially be used in breast cancer treatment due to its inhibitory effect on estrone sulfatase . They convert sulfated steroid precursors to estrogen during pregnancy.
- Associated Conditions
- Polycystic Ovarian Syndrome (PCOS)
- Associated Therapies
- Transdermal contraception therapy
Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women
- Conditions
- HIV InfectionsPregnancy
- First Posted Date
- 2005-08-02
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 32
- Registration Number
- NCT00125983
- Locations
- 🇺🇸
Beth Israel Med. Ctr., ACTU, New York, New York, United States
🇺🇸Univ. of Hawaii at Manoa, Leahi Hosp., Honolulu, Hawaii, United States
🇺🇸Weill Med. College of Cornell Univ., The Cornell CTU, New York, New York, United States
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