Norelgestromin
- Generic Name
- Norelgestromin
- Brand Names
- Evra, Xulane, Zafemy
- Drug Type
- Small Molecule
- Chemical Formula
- C21H29NO2
- CAS Number
- 53016-31-2
- Unique Ingredient Identifier
- R0TAY3X631
- Background
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
- Indication
Norelgestromin is used for contraception and menopausal hormonal therapy. Norelgestromin may potentially be used in breast cancer treatment due to its inhibitory effect on estrone sulfatase . They convert sulfated steroid precursors to estrogen during pregnancy.
- Associated Conditions
- Polycystic Ovarian Syndrome (PCOS)
- Associated Therapies
- Transdermal contraception therapy
Can Evra Patch Solve Teen Pregnancy
Eswatini faces high adolescent pregnancy rates; SRH programs struggle with shortages and health literacy. Proposing Evra Patch as a contraceptive option for adolescents, it delivers hormones to prevent pregnancy, applied weekly. Offering a reliable method can improve adherence and reduce unintended pregnancies, easing healthcare pressure. Evra Patch approved by EMA and FDA, though FDA warns of higher estrogen levels and potential side effects.
Drug Development Updates
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