MedPath

Vilazodone

Generic Name
Vilazodone
Brand Names
Viibryd
Drug Type
Small Molecule
Chemical Formula
C26H27N5O2
CAS Number
163521-12-8
Unique Ingredient Identifier
S239O2OOV3
Background

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors. Vilazodone may also be associated with less sexual dysfunction and weight gain. Vilazodone was given FDA approval on January 21, 2011.

Indication

用于治疗成人重度抑郁症(MDD)。

Associated Conditions
Major Depressive Disorder (MDD)

Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder

Conditions
Major Depressive Disorder
Interventions
First Posted Date
2017-07-26
Last Posted Date
2017-07-26
Lead Sponsor
Huashan Hospital
Target Recruit Count
80
Registration Number
NCT03230682
Locations
🇨🇳

Dept. of Neurology, Huashan Hospital, Fudan University, Shanghai, Shanghai, China

Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder

Completed
Conditions
Bipolar Disorder
Pregnancy Complications
Interventions
Drug: Antipsychotic
Drug: Antipsychotic and Antidepressant
First Posted Date
2016-11-22
Last Posted Date
2018-05-11
Lead Sponsor
Western University, Canada
Target Recruit Count
3357
Registration Number
NCT02970721

Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder

Conditions
Major Depressive Disorder
Interventions
First Posted Date
2016-10-14
Last Posted Date
2016-10-17
Lead Sponsor
University Medical Center Groningen
Target Recruit Count
10000
Registration Number
NCT02934035

Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies

Terminated
Conditions
Bipolar Disorder
First Posted Date
2016-09-08
Last Posted Date
2024-03-12
Lead Sponsor
University of New Mexico
Target Recruit Count
1037352
Registration Number
NCT02893371
Locations
🇺🇸

Christophe G Lambert, Albuquerque, New Mexico, United States

Multimodal Imaging of ECT Effects

Completed
Conditions
Major Depressive Disorder
Interventions
Procedure: electroconvulsive therapy
First Posted Date
2016-08-18
Last Posted Date
2022-11-01
Lead Sponsor
Charite University, Berlin, Germany
Target Recruit Count
68
Registration Number
NCT02871141
Locations
🇩🇪

Charité, Berlin, Germany

Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia

Completed
Conditions
Schizophrenia
Schizoaffective Disorder
Interventions
Drug: Mood stabilizer
Drug: Antipsychotic
First Posted Date
2016-05-18
Last Posted Date
2024-05-01
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
81921
Registration Number
NCT02775864

Can Acupuncture Treat Post-stroke Depression?

Not Applicable
Completed
Conditions
Stroke
Depression
Stroke Sequelae
Interventions
Procedure: Dense cranial electroacupuncture stimulation
Procedure: Body acupuncture
Procedure: Least acupuncture stimulation
Other: Rehabilitation
First Posted Date
2015-12-31
Last Posted Date
2019-05-20
Lead Sponsor
The University of Hong Kong
Target Recruit Count
91
Registration Number
NCT02644161
Locations
🇭🇰

Department of Rehabilitation, Kowloon Hospital, Kowloon, Hong Kong

🇭🇰

Division of Rehabilitation Medicine, Tung Wah Hospital., Sheung Wan, Hong Kong

Predictors of the Outcome of Late Life Depression

Conditions
Major Depression
Interventions
Other: Treatment as usual (only pharmacological treatment).
Other: Psychoeducation
First Posted Date
2015-05-12
Last Posted Date
2018-05-24
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
120
Registration Number
NCT02441387
Locations
🇧🇷

University of São Paulo, Faculty of Medicine, Institute and Department of Psychiatry, São Paulo, Brazil

A Study of Vilazodone in Pediatric Patients With Major Depressive Disorder

Phase 3
Completed
Conditions
Major Depressive Disorder
Interventions
First Posted Date
2015-05-06
Last Posted Date
2019-09-11
Lead Sponsor
Forest Laboratories
Target Recruit Count
330
Registration Number
NCT02436239
Locations
🇺🇸

ATP Clinical Research, Costa Mesa, California, United States

🇺🇸

Psychiatric Associates, Overland Park, Kansas, United States

🇺🇸

Pharmsite Research Inc., Baltimore, Maryland, United States

and more 52 locations

Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)

Phase 3
Completed
Conditions
Major Depressive Disorder
Interventions
First Posted Date
2015-02-26
Last Posted Date
2019-10-01
Lead Sponsor
Forest Laboratories
Target Recruit Count
473
Registration Number
NCT02372799
Locations
🇺🇸

Harmonex Neuroscience Research, Dothan, Alabama, United States

🇺🇸

Woodland International Research Group, INC, Little Rock, Arkansas, United States

🇺🇸

ATP Clinical Research, Costa Mesa, California, United States

and more 56 locations
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