Praziquantel

Generic Name
Praziquantel
Brand Names
Biltricide
Drug Type
Small Molecule
Chemical Formula
C19H24N2O2
CAS Number
55268-74-1
Unique Ingredient Identifier
6490C9U457
Background

An anthelmintic used in most schistosome and many cestode infestations.

Indication

For the treatment of infections due to all species of schistosoma.

Associated Conditions
Cestode infections, Cysticercosis, Liver fluke infection, Trematode infections, Schistosoma infection
Associated Therapies
-

Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children

First Posted Date
2019-03-28
Last Posted Date
2021-04-05
Lead Sponsor
Institute of Tropical Medicine, Belgium
Target Recruit Count
726
Registration Number
NCT03893097
Locations
🇸🇳

Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formation (IRESSEF), Dakar, Senegal

Schistosomiasis Diagnosis Using a CAA Antigen Test

First Posted Date
2018-12-19
Last Posted Date
2021-07-27
Lead Sponsor
Centre de Recherche Médicale de Lambaréné
Target Recruit Count
100
Registration Number
NCT03779347
Locations
🇬🇦

Centre de Recherches Médicales de Lambaréné, Lambaréné, Moyen Ogooué, Gabon

🇬🇦

Centre de Recherches Medicales de Lambaréné, Lambaréné, Gabon

Praziquantel in Children Under Age 4

First Posted Date
2018-08-21
Last Posted Date
2022-05-20
Lead Sponsor
Rhode Island Hospital
Target Recruit Count
600
Registration Number
NCT03640377
Locations
🇬🇧

London School of Tropical Hygiene and Medicine, London, United Kingdom

🇺🇬

Medical Research Council, Entebbe, Uganda

Praziquantel Bioequivalence Study

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-02-19
Last Posted Date
2019-09-18
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
60
Registration Number
NCT03437447
Locations
🇲🇽

Clínica de Enfermedades Crónicas y de Procedimientos Especiales, Sociedad Civil (SC), México, Mexico

Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-08-25
Last Posted Date
2016-10-27
Lead Sponsor
University of Toronto
Target Recruit Count
34
Registration Number
NCT02878564
Locations
🇺🇬

UVRI-IAVI HIV Vaccine program, Entebbe, Wakiso, Uganda

Schistosoma Mansoni in Mwanza Region, Tanzania

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2014-06-13
Last Posted Date
2017-02-10
Lead Sponsor
DBL -Institute for Health Research and Development
Target Recruit Count
37500
Registration Number
NCT02162875
Locations
🇹🇿

National Institute for Mediacal Research, Mwanza, Lake Region, Tanzania

Schistosoma Mansoni Morbidity in Children Aged 1-5 Years

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-07-17
Last Posted Date
2014-09-17
Lead Sponsor
Makerere University
Target Recruit Count
800
Registration Number
NCT01901484
Locations
🇺🇬

Child Health & Development Centre, College of Health Sciences , Makerere University, Kampala, Uganda

Impact IPT With Sulfadoxine-pyrimethamine or Sulfadoxine-pyrimethamine Plus Piperaquine in Schoolchildren

First Posted Date
2012-11-07
Last Posted Date
2014-02-04
Lead Sponsor
Universiteit Antwerpen
Target Recruit Count
616
Registration Number
NCT01722539
Locations
🇨🇬

Mokali health area of Biyela health zone, in Kinshasa province., Kinshasa, Kinshasa province, Congo

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