Lactobacillus

Generic Name: Lactobacillus

Indication: 主要用于消化不良以及场内异常发酵，小儿饮食不当引起的腹泻及营养不良等；也用于使用抗生素及放、化疗后引起的菌群失调性腹泻及急性肠胃炎、腹泻、痢疾等。

Clinical Trials

A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pH

Phase 4

Conditions: Bacterial Vaginosis

Interventions: Drug: Lactobacillus Species
Other: Placebo

First Posted Date: 2021-09-28

Last Posted Date: 2022-05-02

Lead Sponsor: Vedic Lifesciences Pvt. Ltd.

Target Recruit Count: 75

Registration Number: NCT05060029

Locations: 🇮🇳
Shinde Medicare Hospital, Mumbai, Maharashtra, India
🇮🇳
Shubham Sudbhawana Superspeciality Hospital,, Varanasi, Uttar Pradesh, India
🇮🇳
Saraogi Hospital, Mumbai, Maharashtra, India

and more 2 locations

Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

Phase 2

Completed

Conditions: HIV Infections
Bacterial Vaginosis

Interventions: Drug: Placebo
Drug: LACTIN-V

First Posted Date: 2021-08-26

Last Posted Date: 2024-08-13

Lead Sponsor: University of California, San Francisco

Target Recruit Count: 45

Registration Number: NCT05022212

Locations: 🇿🇦
FRESH (Females Rising through Education, Support and Health) Clinical Research Site, Durban, KwaZulu-Natal, South Africa

Efficacy of Oral Supplementation of Probiotics in Children With Atopic Dermatitis

Not Applicable

Completed

Conditions: Atopic Dermatitis

Interventions: Drug: Probiotic sachet containing mixture of four strains i.e.Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium longum, and Saccharomyces boulardii
Drug: Conventional treatment

First Posted Date: 2021-01-13

Last Posted Date: 2021-12-16

Lead Sponsor: B.P. Koirala Institute of Health Sciences

Target Recruit Count: 98

Registration Number: NCT04706559

Locations: 🇳🇵
B.P. Koirala Institute of Health Sciences, Dharān Bāzār, Nepal

The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis

Phase 1

Completed

Conditions: Chronic Periodontitis

Interventions: Drug: Lactobacillus Reuteri Oral Drops
Procedure: Scaling and root planing

First Posted Date: 2021-01-06

Last Posted Date: 2021-01-06

Lead Sponsor: Tanta University

Target Recruit Count: 12

Registration Number: NCT04697199

Locations: 🇪🇬
Ghadeer, Tanta, Egypt

Probiotics and Irritable Bowel Syndrome

Not Applicable

Completed

Conditions: Irritable Bowel Syndrome

Interventions: Drug: lactobacillus delbruekii

First Posted Date: 2020-10-01

Last Posted Date: 2020-10-05

Lead Sponsor: Ain Shams University

Target Recruit Count: 90

Registration Number: NCT04572932

Locations: 🇪🇬
Tropical medicine department, Cairo, Egypt

The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants

Phase 2

Conditions: Necrotizing Enterocolitis
Sepsis

Interventions: Drug: Lactobacillus Reuteri DSM 17938
Drug: Placebo

First Posted Date: 2020-09-09

Last Posted Date: 2020-09-09

Lead Sponsor: Children's Hospital and Institute of Child Health, Multan

Target Recruit Count: 120

Registration Number: NCT04541771

Antipsychotic Effects of Probiotics and Prebiotics on Patients With Schizophrenia

Not Applicable

Conditions: Schizophrenia

Interventions: Dietary Supplement: maltodextrin
Dietary Supplement: Prebiotics (Combined inulin and maltodextrin tables)
Drug: Probiotics（Live combined bifidobacteria, lactobacillus and maltodextrin tables)

First Posted Date: 2020-03-02

Last Posted Date: 2022-04-08

Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Target Recruit Count: 200

Registration Number: NCT04291469

Locations: 🇨🇳
First Affiliated Hospital of Xi'an Jiao tong University, Xi'an, Shanxi, China

Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis

Not Applicable

Completed

Conditions: Major Trauma
Sepsis

Interventions: Drug: intravenous vitamin C plus thiamine
Drug: oral lactobacillus probiotics plus intramuscular cholecalciferol

First Posted Date: 2020-01-02

Last Posted Date: 2021-10-11

Lead Sponsor: Mansoura University

Target Recruit Count: 112

Registration Number: NCT04216459

Locations: 🇪🇬
Mansoura University-Emergency hospital-ICU, Mansoura, Egypt

Lactobacillus LB as Treatment for Irritable Bowel Syndrome With Predominance of Diarrhea (IBS-D)

Phase 4

Completed

Conditions: Irritable Bowel Syndrome With Diarrhea

Interventions: Drug: lactobacillus LB
Other: placebo

First Posted Date: 2019-08-13

Last Posted Date: 2023-03-06

Lead Sponsor: Hospital General de Mexico

Target Recruit Count: 177

Registration Number: NCT04053790

Locations: 🇲🇽
Hospital General de Mexico, Mexico City, Choose Any State/Province, Mexico

The Role of Probiotics in Improving Quality of Life in Women With Functional Constipation

Phase 2

Completed

Conditions: Constipation - Functional

Interventions: Drug: Lactobacillus plantarum IS-10506
Drug: Placebo

First Posted Date: 2019-02-04

Last Posted Date: 2019-02-05

Lead Sponsor: Fakultas Kedokteran Universitas Indonesia

Target Recruit Count: 76

Registration Number: NCT03829358

Locations: 🇮🇩
Puskesmas Petamburan, Jakarta, DKI Jakarta, Indonesia

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