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MK-8353

Generic Name
MK-8353

Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014)

Phase 1
Completed
Conditions
Solid Tumors
Interventions
First Posted Date
2018-11-19
Last Posted Date
2023-07-27
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
30
Registration Number
NCT03745989
Locations
🇺🇸

Florida Cancer Specialists ( Site 7000), Sarasota, Florida, United States

🇺🇸

Next Oncology ( Site 0001), San Antonio, Texas, United States

🇨🇦

Princess Margaret Cancer Centre ( Site 0012), Toronto, Ontario, Canada

and more 2 locations

Study of MK-8353 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Malignancies (MK-8353-013)

Phase 1
Terminated
Conditions
Neoplasms
Colorectal Cancer
Interventions
First Posted Date
2016-11-23
Last Posted Date
2024-11-21
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
111
Registration Number
NCT02972034
Locations
🇨🇦

Merck Canada, Kirkland, Quebec, Canada

🇺🇸

Call for Information (Investigational Site 0002), Grand Rapids, Michigan, United States

🇺🇸

Call for Information (Investigational Site 0001), Nashville, Tennessee, United States

A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)

Phase 1
Terminated
Conditions
Tumor, Solid
Interventions
First Posted Date
2011-05-23
Last Posted Date
2020-04-02
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
25
Registration Number
NCT01358331
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