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CT041

Generic Name
CT041
Drug Type
Biotech
Background

CT041 is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).

A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer

Phase 1
Recruiting
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2023-06-20
Last Posted Date
2024-05-28
Lead Sponsor
CARsgen Therapeutics Co., Ltd.
Target Recruit Count
20
Registration Number
NCT05911217
Locations
🇨🇳

Fudan University Shanghai Cancer Hospital, Shanghai, Shanghai, China

🇨🇳

Hunan Provincial People's Hospital, Changsha, Hunan, China

🇨🇳

Ruijin Hospital, affiliated to Shanghai Jiaotong University, school of medicine, Shanghai, Shanghai, China

and more 5 locations

Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection

Phase 1
Recruiting
Conditions
Gastric Adenocarcinoma
Pancreatic Cancer
Gastroesophageal Junction Adenocarcinoma
Interventions
Drug: Physician's Choice(Paclitaxel or Irinotecan or Apatinib or Anti-PD-1 antibody)
First Posted Date
2020-10-09
Last Posted Date
2024-03-06
Lead Sponsor
CARsgen Therapeutics Co., Ltd.
Target Recruit Count
192
Registration Number
NCT04581473
Locations
🇨🇳

The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China

🇨🇳

Anhui Provincial Cancer Hospital, Hefei, Anhui, China

🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

and more 21 locations

Claudin18.2 CAR-T (CT041) in Patients with Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers

Phase 1
Active, not recruiting
Conditions
Gastric Cancer
Pancreatic Cancer
Interventions
First Posted Date
2020-05-27
Last Posted Date
2025-01-08
Lead Sponsor
CARsgen Therapeutics Co., Ltd.
Target Recruit Count
110
Registration Number
NCT04404595
Locations
🇺🇸

Karmanos Cancer Center, Detroit, Michigan, United States

🇺🇸

University of Southern California, Los Angeles, California, United States

🇺🇸

UCSD, San Diego, California, United States

and more 13 locations
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