Aminophylline
- Generic Name
- Aminophylline
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C16H24N10O4
- CAS Number
- 317-34-0
- Unique Ingredient Identifier
- 27Y3KJK423
- Background
Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, ch...
- Indication
For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
- Associated Conditions
- Acute Exacerbation of Chronic Bronchitis (AECB), Asthma, Bronchial Asthma, Bronchospasm, Chronic Bronchitis, Exacerbation of asthma
- Associated Therapies
- -
Aminophylline for Patients With Post-Dural Puncture Headache
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2016-10-31
- Target Recruit Count
- 126
- Registration Number
- NCT02522013
- Locations
- 🇨🇳
Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan, China
🇨🇳Jinzhou central hospital, Jinzhou, Liaoning, China
🇨🇳Suzhou municipal hospital, Suzhou, Anhui, China
A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics
- Conditions
- First Posted Date
- 2014-10-21
- Last Posted Date
- 2015-10-28
- Lead Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
- Target Recruit Count
- 5
- Registration Number
- NCT02270827
- Locations
- 🇬🇧
Royal Brompton Hospital, London, United Kingdom
Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant
- Conditions
- Interventions
- First Posted Date
- 2013-01-03
- Last Posted Date
- 2019-03-05
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 50
- Registration Number
- NCT01759862
- Locations
- 🇺🇸
Lucile Packard Children's Hospital at Stanford, Stanford, California, United States
Rapid Acclimatization to Hypoxia at Altitude
- Conditions
- Interventions
- First Posted Date
- 2012-10-05
- Last Posted Date
- 2014-10-24
- Lead Sponsor
- Colorado State University
- Target Recruit Count
- 41
- Registration Number
- NCT01702025
- Locations
- 🇺🇸
Colorado State University, Dept. of Health and Exercise Science, Fort Collins, Colorado, United States
Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2012-05-09
- Last Posted Date
- 2012-10-30
- Lead Sponsor
- Ospedale Misericordia e Dolce
- Target Recruit Count
- 250
- Registration Number
- NCT01594489
- Locations
- 🇮🇹
Ospedale Misericordia e Dolce, Prato, Italy
Safety Evaluation of Aminophylline and Methazolamide
- Conditions
- Interventions
- First Posted Date
- 2012-04-27
- Last Posted Date
- 2017-02-10
- Lead Sponsor
- Poudre Valley Health System
- Target Recruit Count
- 16
- Registration Number
- NCT01587027
- Locations
- 🇺🇸
Medical Center of the Rockies, Loveland, Colorado, United States
The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2012-02-10
- Last Posted Date
- 2014-01-16
- Lead Sponsor
- Thies Schroeder
- Target Recruit Count
- 18
- Registration Number
- NCT01530464
- Locations
- 🇺🇸
Duke Clinical Research Unit, Durham, North Carolina, United States
Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging
- First Posted Date
- 2011-04-15
- Last Posted Date
- 2023-01-26
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 300
- Registration Number
- NCT01336140
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Adenosine Activity in Producing Venoarteriolar Reflexes
- First Posted Date
- 2011-01-20
- Last Posted Date
- 2011-01-20
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Registration Number
- NCT01280071
Study With Aminophylline to Attenuate of the Side Effects of Regadenoson
- Conditions
- Interventions
- First Posted Date
- 2010-11-30
- Last Posted Date
- 2023-03-13
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 248
- Registration Number
- NCT01250496
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.