Cannabidiol
- Generic Name
- Cannabidiol
- Brand Names
- Epidiolex, Sativex, Epidyolex
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O2
- CAS Number
- 13956-29-1
- Unique Ingredient Identifier
- 19GBJ60SN5
- Background
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact medical implications are currently being investig...
- Indication
When used in combination with delta-9-tetrahydrocannabinol as the product Sativex, cannabidiol was given a standard marketing authorization (ie. a Notice of Compliance (NOC)) by Health Canada for the following indications:
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- Associated Conditions
- Multiple Sclerosis, Seizures, Severe Pain, Moderate Pain
- Associated Therapies
- -
Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study
- Conditions
- Interventions
- First Posted Date
- 2015-07-08
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Central Institute of Mental Health, Mannheim
- Target Recruit Count
- 60
- Registration Number
- NCT02492074
- Locations
- 🇩🇪
Central Institute of Mental Health, Mannheim, BW, Germany
Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids
- Conditions
- Interventions
- First Posted Date
- 2015-07-01
- Last Posted Date
- 2015-08-17
- Lead Sponsor
- Central Institute of Mental Health, Mannheim
- Target Recruit Count
- 60
- Registration Number
- NCT02487381
- Locations
- 🇩🇪
Central Institute of Mental Health, Mannheim, BW, Germany
Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease
- Conditions
- Interventions
- First Posted Date
- 2015-06-23
- Last Posted Date
- 2015-06-23
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 10
- Registration Number
- NCT02478424
Treatment of Drug Resistant Epilepsy
- Conditions
- First Posted Date
- 2015-06-03
- Last Posted Date
- 2019-01-22
- Lead Sponsor
- University of Florida
- Registration Number
- NCT02461706
- Locations
- 🇺🇸
University of Flordia CRC, Gainesville, Florida, United States
🇺🇸Nicklaus Children's Hospital, Miami Children's Health System, Miami, Florida, United States
Cannabidiol for the Treatment of Severe (Grades III/IV) Acute Graft-versus-host Disease
- Conditions
- Interventions
- First Posted Date
- 2015-03-19
- Last Posted Date
- 2015-03-19
- Lead Sponsor
- moshe yeshurun
- Target Recruit Count
- 10
- Registration Number
- NCT02392780
- Locations
- 🇮🇱
Davidof Cancer Center, Beilinson hospital, Rabin medical center, Petach Tikva, Israel
Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome
- First Posted Date
- 2015-01-07
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- Anne Comi, MD
- Target Recruit Count
- 5
- Registration Number
- NCT02332655
- Locations
- 🇺🇸
Kennedy Krieger Institute, Baltimore, Maryland, United States
Effects of THC and CBD on Human Episodic Memory Function
- Conditions
- Interventions
- First Posted Date
- 2014-11-14
- Last Posted Date
- 2015-01-16
- Lead Sponsor
- Central Institute of Mental Health, Mannheim
- Target Recruit Count
- 20
- Registration Number
- NCT02291562
- Locations
- 🇩🇪
Central Institute of Mental Health, Mannheim, Germany
Processing of Salient Emotional Stimuli as a Function of Tetrahydrocannabinol (THC) and Cannabidiol (CBD)
- Conditions
- Interventions
- First Posted Date
- 2014-11-14
- Last Posted Date
- 2015-01-16
- Lead Sponsor
- Central Institute of Mental Health, Mannheim
- Target Recruit Count
- 20
- Registration Number
- NCT02291536
- Locations
- 🇩🇪
Central Institute of Mental Health, Mannheim, Germany
Cannabidiol (CBD) to 27 Patients (Aged 2 Years - 19 Years) With Drug Resistant Epilepsy
- First Posted Date
- 2014-11-10
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 26
- Registration Number
- NCT02286986
- Locations
- 🇺🇸
University of Utah School of Medicine, Salt Lake City, Utah, United States
The Role of the Endocannabinoid System in Sweet Taste Intensity and Liking
- Conditions
- Interventions
- First Posted Date
- 2014-04-11
- Last Posted Date
- 2017-05-23
- Lead Sponsor
- Wageningen University
- Target Recruit Count
- 10
- Registration Number
- NCT02112292
- Locations
- 🇳🇱
Wageningen University, Wageningen, Gelderland, Netherlands
Drug Development Updates
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