MedPath

Delavirdine

Generic Name
Delavirdine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C22H28N6O3S
CAS Number
136817-59-9
Unique Ingredient Identifier
DOL5F9JD3E
Background

A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.

Indication

用于高效抗逆转录病毒疗法(HAART)的组成药物。

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

Immunologic and Virologic Consequences of Long-Term Highly Active Antiretroviral Therapy (HAART) in Subjects With Moderately Advanced HIV-1 Disease: A Follow-Up Study to ACTG 315

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
34
Registration Number
NCT00000891
Locations
🇺🇸

Case Western Reserve Univ, Cleveland, Ohio, United States

🇺🇸

Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States

🇺🇸

Rush Presbyterian - Saint Luke's Med Ctr, Chicago, Illinois, United States

Virologic and Immunologic Activity of Continued Lamivudine (3TC) vs Delavirdine (DLV) in Combination With Indinavir (IDV) and Zidovudine (ZDV) or Stavudine (d4T) in 3TC-Experienced Subjects

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2013-07-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00000882
Locations
🇺🇸

State of MD Div of Corrections / Johns Hopkins Univ Hosp, Baltimore, Maryland, United States

🇺🇸

Northwestern Univ Med School, Chicago, Illinois, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

and more 28 locations

A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination Therapy

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
471
Registration Number
NCT00000803
Locations
🇺🇸

Bmc Actg Crs, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital ACTG CRS, Boston, Massachusetts, United States

🇺🇸

University of Washington AIDS CRS, Seattle, Washington, United States

and more 29 locations

Randomized, Phase I/II, Dose-Ranging, Open-Label Trial of the Anti-HIV Activity of Delavirdine Mesylate (DLV; U-90,152S)

Phase 1
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
120
Registration Number
NCT00000810
Locations
🇺🇸

Howard University Hosp., Div. of Infectious Diseases, ACTU, Washington, District of Columbia, United States

🇺🇸

Stanford CRS, Stanford, California, United States

🇺🇸

SUNY - Buffalo, Erie County Medical Ctr., Buffalo, New York, United States

and more 7 locations

A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected Patients

Phase 2
Withdrawn
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2015-03-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Registration Number
NCT00001094
Locations
🇺🇸

Willow Clinic, Menlo Park, California, United States

🇺🇸

Stanford Univ Med Ctr, Stanford, California, United States

🇺🇸

Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States

and more 14 locations

A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00000892
Locations
🇺🇸

Cornell Univ Med Ctr, New York, New York, United States

🇺🇸

Mount Sinai Med Ctr, New York, New York, United States

🇺🇸

Univ of Tennessee / E Tennessee Comprehensive Hemophilia Ctr, Knoxville, Tennessee, United States

and more 42 locations
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