MedPath

Etomidate

Generic Name
Etomidate
Brand Names
Amidate
Drug Type
Small Molecule
Chemical Formula
C14H16N2O2
CAS Number
33125-97-2
Unique Ingredient Identifier
Z22628B598
Background

Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.

Indication

Used in the induction of general anesthesia.

Associated Conditions
-
Associated Therapies
General Anesthesia

Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial

Phase 4
Completed
Conditions
Respiratory Arrest
Cardiopulmonary Arrest
Interventions
Drug: Etomidate
Drug: Ketamine
Procedure: Emergency Endotracheal Intubation
Device: Mechanical Ventilation
First Posted Date
2015-12-31
Last Posted Date
2021-12-15
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
801
Registration Number
NCT02643381
Locations
🇺🇸

Parkland Hospital, Dallas, Texas, United States

Effects and Mechanism of Pretreatment With Dexmedetomidine to Etomidate Induce Myoclonus

Phase 4
Conditions
Myoclonus
Interventions
First Posted Date
2015-08-10
Last Posted Date
2015-08-10
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
132
Registration Number
NCT02518789

Comparison the Effects of Etomidate and Sevoflurane During Electroconvulsive Therapy

Phase 4
Completed
Conditions
Anesthesia
ECT
Interventions
First Posted Date
2015-07-16
Last Posted Date
2019-01-23
Lead Sponsor
Inonu University
Target Recruit Count
25
Registration Number
NCT02500225

Helping Stroke Patients With ThermoSuit Cooling

Not Applicable
Terminated
Conditions
Brain Ischemia
Stroke
Interventions
Device: ThermoSuit Cooling Induction
Drug: Magnesium Sulfate
Drug: tPA
Drug: Propofol
Drug: Etomidate
Procedure: Neurothrombectomy
First Posted Date
2015-05-25
Last Posted Date
2023-06-06
Lead Sponsor
Life Recovery Systems
Target Recruit Count
14
Registration Number
NCT02453373
Locations
🇺🇸

Geisinger Medical Center, Danville, Pennsylvania, United States

🇺🇸

U of SC School of Medicine, Columbia, South Carolina, United States

🇺🇸

Tulane University, New Orleans, Louisiana, United States

and more 1 locations

The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial

Phase 4
Conditions
Induced Abortion
Anesthesia
Interventions
First Posted Date
2014-08-05
Last Posted Date
2014-08-05
Lead Sponsor
Third Affiliated Hospital of Zhengzhou University
Target Recruit Count
150
Registration Number
NCT02208596

Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients

First Posted Date
2014-07-28
Last Posted Date
2014-07-28
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
60
Registration Number
NCT02202239

Comparison of Etomidate, Propofol and Etomidate-propofol Combination in Terms of Effects on Haemodynamic Response to Intubation

Phase 4
Completed
Conditions
Induction of Anaesthesia
Interventions
Drug: etomidate-propofol
Drug: etomidate
Drug: propofol
First Posted Date
2014-07-10
Last Posted Date
2014-08-13
Lead Sponsor
T.C. ORDU ÜNİVERSİTESİ
Target Recruit Count
90
Registration Number
NCT02186990
Locations
🇹🇷

Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital, Altınordu, Ordu, Turkey

Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia Induction

Phase 4
Conditions
Bispectral Index
Pediatric
Etomidate
Induction
Interventions
First Posted Date
2014-07-08
Last Posted Date
2014-07-08
Lead Sponsor
Henan Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02182648

The Application of Target Controlled Infusion of Etomidate Combined With Propofol in the Maintenance of Anesthesia During Brain Surgeries

Phase 4
Conditions
Target Controlled Infusion
General Anesthesia
Interventions
First Posted Date
2014-06-25
Last Posted Date
2014-06-25
Lead Sponsor
Henan Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02174120

A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients

Phase 4
Conditions
Hysteroscopy
Hemodynamics
Sedation
Interventions
First Posted Date
2014-05-28
Last Posted Date
2014-05-28
Lead Sponsor
Shaanxi Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02147678
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