Bupropion
- Generic Name
- Bupropion
- Brand Names
- Aplenzin, Auvelity, Budeprion, Contrave, Forfivo, Wellbutrin, Zyban
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18ClNO
- CAS Number
- 34911-55-2
- Unique Ingredient Identifier
- 01ZG3TPX31
- Background
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the upta...
- Indication
Bupropion is indicated for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
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- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Major Depressive Disorder (MDD), Obesity, Seasonal Affective Disorder (SAD)
- Associated Therapies
- Smoking, Cessation, Weight Loss
Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking
- First Posted Date
- 2005-11-03
- Last Posted Date
- 2016-09-23
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 72
- Registration Number
- NCT00248118
- Locations
- 🇺🇸
Teen Tobacco Addiction Research Clinic, NIDA Intramural Research Program, Baltimore, Maryland, United States
Integrated Treatment for Cocaine and Mood Disorders - 1
- Conditions
- First Posted Date
- 2005-09-28
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 140
- Registration Number
- NCT00227812
- Locations
- 🇺🇸
University of Texas Health Sci Cntr Houston, Houston, Texas, United States
The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2007-12-06
- Lead Sponsor
- Affective Neuroscience Laboratory
- Target Recruit Count
- 32
- Registration Number
- NCT00205946
- Locations
- 🇺🇸
The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸Affective Neuroscience Laboratory, Department of Psychology, Harvard University, Cambridge, Massachusetts, United States
Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2005-09-15
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 60
- Registration Number
- NCT00177567
- Locations
- 🇺🇸
University of Pittsubrgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Dynamic Measures of Neurochemistry in Mood Disorders
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2017-04-11
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 42
- Registration Number
- NCT00178828
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Effectiveness of Bupropion in Treating Marijuana Dependent Individuals
- First Posted Date
- 2005-09-02
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 30
- Registration Number
- NCT00142870
- Locations
- 🇺🇸
McLean Hospital, Dept. of Psychiatry, Belmont, Massachusetts, United States
The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1
- Conditions
- Interventions
- First Posted Date
- 2005-08-29
- Last Posted Date
- 2018-05-21
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 45
- Registration Number
- NCT00136747
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Contingent Incentives Plus Bupropion for Smoking in People With Schizophrenia
- First Posted Date
- 2005-08-29
- Last Posted Date
- 2015-10-07
- Lead Sponsor
- Brown University
- Target Recruit Count
- 57
- Registration Number
- NCT00136760
- Locations
- 🇺🇸
Brown University, Providence, Rhode Island, United States
Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2
- First Posted Date
- 2005-08-26
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 73
- Registration Number
- NCT00135785
- Locations
- 🇺🇸
UCLA Medical Center, Los Angeles, California, United States
🇺🇸Rancho Cucamonga Clinic, Rancho Cucamonga, California, United States
Impact of Smoking Cessation on Sleep - 5
- Conditions
- Interventions
- First Posted Date
- 2005-08-22
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 59
- Registration Number
- NCT00132821
- Locations
- 🇺🇸
SRI International, Menlo Park, California, United States
Drug Development Updates
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