Fentanyl

Generic Name
Fentanyl
Brand Names
Abstral, Actiq, Duragesic, Effentora, Fentora, Instanyl, Lazanda, Sublimaze, Subsys, PecFent
Drug Type
Small Molecule
Chemical Formula
C22H28N2O
CAS Number
437-38-7
Unique Ingredient Identifier
UF599785JZ
Background

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia. Fentanyl is related to other opioids like morphine and oxycodone.
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Indication

Fentanyl intravenous or intramuscular injections are indicated for short term analgesia during induction, maintenance, and recovery from general or regional anesthesia. These injections are also used with a neuroleptic for premedication, induction, and as an adjunct to maintenance of anesthesia. Finally, fentanyl intravenous or intramuscular injections are u...

Associated Conditions
Cancer Related Pain (Breakthrough Pain), Severe, Chronic Pain
Associated Therapies
Anesthetic premedication therapy, Anesthetics Agent, General Anesthesia, Induction of anesthesia therapy, Maintenance of anesthesia therapy, Regional Anesthesia therapy

Airway Responses During Desflurane Anesthesia Via a Laryngeal Mask Airway: Effects of Fentanyl Pretreatment

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-01-17
Last Posted Date
2013-03-15
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
100
Registration Number
NCT01277861
Locations
🇺🇸

Ut Southwestern Medical Center At Dallas, Dallas, Texas, United States

Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-01-05
Last Posted Date
2017-06-20
Lead Sponsor
University of Oklahoma
Target Recruit Count
60
Registration Number
NCT01270659
Locations
🇺🇸

Hillcrest Medical Center Emergency Department, Tulsa, Oklahoma, United States

Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction

First Posted Date
2010-12-10
Last Posted Date
2023-12-12
Lead Sponsor
University of California, San Francisco
Target Recruit Count
60
Registration Number
NCT01258296
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

Nasal Fentanyl for Patient Controlled Treatment of Pain in Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-11-25
Last Posted Date
2014-05-12
Lead Sponsor
St. Olavs Hospital
Target Recruit Count
10
Registration Number
NCT01248611
Locations
🇳🇴

St.Olavs University Hospital, Trondheim, Norway

Pain, Opioids and Pro-Inflammatory Immune Responses

First Posted Date
2010-09-28
Last Posted Date
2016-12-29
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
21
Registration Number
NCT01210066
Locations
🇺🇸

UCLA School of Nursing, Los Angeles, California, United States

Comparison of Postoperative Analgesic Effect of Intrathecal Magnesium and Fentanyl Added to Bupivacaine in Patients Undergoing Lower Limb Orthopedic Surgery

First Posted Date
2010-09-21
Last Posted Date
2012-10-11
Lead Sponsor
Qazvin University Of Medical Sciences
Target Recruit Count
90
Registration Number
NCT01205997
Locations
🇮🇷

Qazvin university of medical science, Qazvin, Iran, Islamic Republic of

Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery

First Posted Date
2010-09-03
Last Posted Date
2012-06-29
Lead Sponsor
Mayo Clinic
Target Recruit Count
13
Registration Number
NCT01195103
Locations
🇺🇸

Mayo Clinic, Phoenix, Arizona, United States

Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement

First Posted Date
2010-08-25
Last Posted Date
2014-04-01
Lead Sponsor
Nationwide Children's Hospital
Target Recruit Count
100
Registration Number
NCT01188551
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2010-07-23
Last Posted Date
2012-06-04
Lead Sponsor
University of Utah
Registration Number
NCT01169025
Locations
🇺🇸

University of Utah Medical Center, Salt Lake City, Utah, United States

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