MedPath

Sulanemadlin

Generic Name
Sulanemadlin
Drug Type
Biotech
CAS Number
1451199-98-6
Unique Ingredient Identifier
6BGF28R54M

A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer

Phase 1
Terminated
Conditions
Prevention of Chemotherapy-induced Myelosuppression
Interventions
First Posted Date
2022-11-18
Last Posted Date
2023-02-27
Lead Sponsor
Aileron Therapeutics, Inc.
Target Recruit Count
6
Registration Number
NCT05622058
Locations
🇧🇬

MBAL University Hospital OOD, Panagyurishte, Bulgaria

🇺🇸

Southern Oncology Specialists, Huntersville, North Carolina, United States

🇺🇸

Oncology and Hematology Associates of West Broward, Tamarac, Florida, United States

and more 11 locations

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

Phase 1
Terminated
Conditions
Small-cell Lung Cancer
Non Small Cell Lung Cancer
Interventions
First Posted Date
2019-07-17
Last Posted Date
2022-10-10
Lead Sponsor
Aileron Therapeutics, Inc.
Target Recruit Count
35
Registration Number
NCT04022876
Locations
🇺🇸

Mount Sinai Cancer Research Program, Miami, Florida, United States

🇺🇸

Regional Medical Oncolgy Center, Wilson, North Carolina, United States

🇺🇸

Gabrail Cancer Institute, Canton, Ohio, United States

and more 25 locations

Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer

Phase 1
Completed
Conditions
Leukemia
Brain Tumor
Solid Tumor
Lymphoma
Interventions
First Posted Date
2018-08-31
Last Posted Date
2025-02-14
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
21
Registration Number
NCT03654716
Locations
🇺🇸

UCSF Benioff Children's Hospital, San Francisco, California, United States

🇺🇸

Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 1 locations

Safety Study of ALRN-6924 in Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

Phase 1
Completed
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Interventions
Drug: ALRN-6924 in combination with cytarabine
First Posted Date
2016-09-21
Last Posted Date
2019-11-19
Lead Sponsor
Aileron Therapeutics, Inc.
Target Recruit Count
55
Registration Number
NCT02909972

ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas

Phase 1
Completed
Conditions
Lymphoma
Peripheral T-Cell Lymphoma
Solid Tumor
Interventions
First Posted Date
2014-10-15
Last Posted Date
2020-07-14
Lead Sponsor
Aileron Therapeutics, Inc.
Target Recruit Count
149
Registration Number
NCT02264613
© Copyright 2025. All Rights Reserved by MedPath