MedPath

CT103A

Generic Name
CT103A
Drug Type
Biotech
Background

CT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.

A Study of a Fully Human BCMA-targeting CAR (CT103A) Combined With Selinexor in Patients With Relapsed/Refractory Extramedullary Multiple Myeloma

Phase 1
Conditions
Extramedullary Multiple Myeloma
Interventions
First Posted Date
2022-01-21
Last Posted Date
2022-05-24
Lead Sponsor
Chunrui Li
Target Recruit Count
20
Registration Number
NCT05201118
Locations
🇨🇳

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hu Bei, China

A Phase 1/2 Study of a Fully Human BCMA-targeting CAR (CT103A) in Patients With Relapsed/Refractory Multiple Myeloma (FUMANBA-1)

Phase 1
Conditions
Multiple Myeloma
Interventions
First Posted Date
2021-10-04
Last Posted Date
2021-11-23
Lead Sponsor
Nanjing IASO Biotechnology Co., Ltd.
Target Recruit Count
132
Registration Number
NCT05066646
Locations
🇨🇳

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

🇨🇳

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

🇨🇳

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

and more 11 locations

Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System

Early Phase 1
Recruiting
Conditions
Idiopathic Inflammatory Myopathies
Neuromyelitis Optica Spectrum Disorder
Autoimmune Diseases of the Nervous System
Myasthenia Gravis
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
POEMS Syndrome
Autoimmune Diseases
Multiple Sclerosis
Autoimmune Encephalitis
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Interventions
First Posted Date
2020-09-23
Last Posted Date
2024-10-30
Lead Sponsor
Tongji Hospital
Target Recruit Count
36
Registration Number
NCT04561557
Locations
🇨🇳

Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China

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