MedPath

CX157

Generic Name
CX157
Drug Type
Small Molecule
Unique Ingredient Identifier
O6L62LZJ0Q
Background

CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor of MAO-A designed to have improved oral bioavailability and reduced clearance compared to previous MAO-A inhibitors of this class.

Indication

Anxiety Disorders I,

Depression I

Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers

Phase 1
Completed
Conditions
Major Depressive Disorder
Interventions
Other: Placebo
First Posted Date
2012-07-04
Last Posted Date
2012-07-04
Lead Sponsor
CeNeRx BioPharma Inc.
Target Recruit Count
12
Registration Number
NCT01633437
Locations
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Comprehensive Phase One, Miramar, Florida, United States

Efficacy, Safety and Tolerability of CX157 in Treatment Resistant Depression

Phase 2
Completed
Conditions
Treatment Resistant Depression
Interventions
First Posted Date
2010-11-24
Last Posted Date
2012-07-10
Lead Sponsor
CeNeRx BioPharma Inc.
Target Recruit Count
360
Registration Number
NCT01246908
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Gulfcoast Clinical Research Center, Fort Myers, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Richard H. Weisler, M.D. and Associates, Raleigh, North Carolina, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of South Florida College of Medicine Psychiatry Center, Tampa, Florida, United States

and more 26 locations

A Study of CX157 (TriRima) for the Treatment of Depression

Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
First Posted Date
2008-08-22
Last Posted Date
2012-06-27
Lead Sponsor
CeNeRx BioPharma Inc.
Target Recruit Count
285
Registration Number
NCT00739908
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Southwestern Research, Inc., Beverly Hills, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Capital Clinical Research Associates, Rockville, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Richard H. Weisler, M.D., P.A., Raleigh, North Carolina, United States

and more 11 locations
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