Avacopan
- Generic Name
- Avacopan
- Brand Names
- Tavneos
- Drug Type
- Small Molecule
- Chemical Formula
- C33H35F4N3O2
- CAS Number
- 1346623-17-3
- Unique Ingredient Identifier
- O880NM097T
- Background
Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified by the presence of ANCAs in the serum. The full spectrum of AAV includes granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinoph...
- Indication
Avacopan is indicated for the adjunctive treatment of adult patients with severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis and microscopic polyangiitis; GPA/MPA) in combination with standard therapy including glucocorticoids. Avacopan does not eliminate the need for glucocorticoids.
...
- Associated Conditions
- Severe, active Granulomatosis With Polyangiitis, Severe, active Microscopic Polyangiitis (MPA), Microscopic Polyangiitis (MPA), Severe Anti-neutrophil cytoplasmic antibody positive vasculitis, Granulomatosis With Polyangiitis
- Associated Therapies
- -
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.