Chlorpheniramine

Generic Name
Chlorpheniramine
Brand Names
Aller-chlor, Allerest PE, Children's Nyquil Cold and Cough, Codar Ar, Coricidin Hbp Cold & Flu, Coricidin Hbp Cough and Cold, Dimetapp Long Acting Cough Plus Cold, Robitussin Pediatric Cough & Cold LA, Scot-tussin Sugar Free DM, Sudogest, Tussicaps, Tussionex, Tuxarin, Tuzistra, Wal-finate
Drug Type
Small Molecule
Chemical Formula
C16H19ClN2
CAS Number
132-22-9
Unique Ingredient Identifier
3U6IO1965U
Background

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

Indication

For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.

Associated Conditions
Allergic Conjunctivitis (AC), Allergic Contact Dermatitis, Allergic Reaction, Allergic Rhinitis (AR), Allergic cough, Allergies caused by Serum, Allergy to Tree Pollen, Allergy to vaccine, Angioneurotic Edema, Asthma, Bronchial Asthma, Bronchitis, Common Cold, Conjunctival congestion, Conjunctivitis, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Drug Allergy, Epiphora, Eye allergy, Fever, Flu caused by Influenza, Food Allergy, Headache, Headache caused by Allergies, House Dust Mite Allergy, Itching of the nose, Itching of the throat, Migraine, Nasal Congestion, Nasal Congestion caused by Common Cold, Productive cough, Pruritus, Rash, Rhinorrhoea, Seasonal Allergic Conjunctivitis, Sinus Congestion, Sinusitis, Sneezing, Transfusion Reactions, Upper Respiratory Tract Infection, Upper respiratory tract congestion, Upper respiratory tract hypersensitivity reaction, site unspecified, Urticaria, Vasomotor Rhinitis, Acute Rhinitis, Allergic purpura, Conjunctival hyperemia, Dry cough, Excess mucus or phlegm, Itchy throat, Mild bacterial upper respiratory tract infections, Ocular hyperemia, Throat inflammation, Upper respiratory symptoms, Watery itchy eyes
Associated Therapies
Airway secretion clearance therapy

Efficacy of Placebo Versus Chlorpheniramine for the Prevention of Allergic Transfusion Reactions.

First Posted Date
2020-12-30
Last Posted Date
2023-11-28
Lead Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Target Recruit Count
6642
Registration Number
NCT04688736
Locations
🇨🇳

Regenerative Medicine Center, Tianjin, Tianjin, China

🇨🇳

Anhui Provincial Hospital, Hefei, Anhui, China

🇨🇳

The Second Affilated Hospital of Shandong First Medical University, Tai'an, Shandong, China

and more 1 locations

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

First Posted Date
2014-02-19
Last Posted Date
2019-07-05
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
58
Registration Number
NCT02065336
Locations
🇭🇰

Prince of Wales Hospital, Shatin, Hong Kong

🇭🇰

Queen Mary Hospital, Pokfulam, Hong Kong

Study Evaluating Chlorpheniramine Maleate Liquid in Children and Adolescents

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-02-05
Last Posted Date
2020-10-23
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
36
Registration Number
NCT00837837
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