Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
Oral Calcitriol for Reduction of Mild Proteinuria in Patients With CKD
- First Posted Date
- 2013-03-29
- Last Posted Date
- 2013-03-29
- Lead Sponsor
- Huashan Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT01820832
- Locations
- 🇨🇳
Huashan Hospital, Fudan University, Shanghai, Shanghai, China
Paricalcitol Effect on Anemia in CKD
- Conditions
- Interventions
- First Posted Date
- 2013-01-15
- Last Posted Date
- 2014-07-30
- Lead Sponsor
- Federico II University
- Target Recruit Count
- 60
- Registration Number
- NCT01768351
- Locations
- 🇮🇹
Federico II University, Naples, Italy
The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels
- Conditions
- Interventions
- First Posted Date
- 2013-01-10
- Last Posted Date
- 2013-01-10
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 88
- Registration Number
- NCT01765010
- Locations
- 🇰🇷
Seoul National University Medical School, Seoul, Korea, Republic of
Effect of Phosphate Binders on FGF-23 With Concurrent Calcitriol
- Conditions
- Interventions
- First Posted Date
- 2012-12-12
- Last Posted Date
- 2013-02-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT01748396
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol
- Conditions
- Interventions
- First Posted Date
- 2012-11-12
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Winthrop University Hospital
- Target Recruit Count
- 16
- Registration Number
- NCT01725113
- Locations
- 🇺🇸
Winthrop University Hospital, Mineola, New York, United States
Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis
- First Posted Date
- 2012-09-21
- Last Posted Date
- 2020-11-10
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 67
- Registration Number
- NCT01689441
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy
- First Posted Date
- 2012-08-27
- Last Posted Date
- 2014-02-13
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 276
- Registration Number
- NCT01673204
- Locations
- 🇰🇷
Seoul National University Boramae Medical Center, Seoul, Korea, Republic of
🇰🇷Seoul National University Hospital, Seoul, Korea, Republic of
The VALIDATE-D Study
- First Posted Date
- 2012-07-06
- Last Posted Date
- 2017-04-11
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 41
- Registration Number
- NCT01635062
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Effect of Vitamin D Supplement on Osteoprotegin Expression and Disease Progression in Patients With Chronic Kidney Disease Stage 1 and 2
- Conditions
- Interventions
- First Posted Date
- 2012-03-22
- Last Posted Date
- 2015-06-08
- Lead Sponsor
- Taixing People's Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT01561222
- Locations
- 🇨🇳
Taixing People's Hospital, Taixing, Jiangsu, China
Anti-proteinuric Effect of Calcitriol in Non-diabetic Kidney Disease Patients
- First Posted Date
- 2012-01-19
- Last Posted Date
- 2012-04-10
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT01512862
- Locations
- 🇰🇷
SMG-SNU Boramae Medical Center, Seoul, Korea, Republic of
🇰🇷Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Korea, Republic of
🇰🇷Seoul National University Hospital, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.