Uprosertib

Overview

Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.

Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.

No indication information available.

No associated conditions information available.

Title	Posted	Study ID	Phase	Status	Sponsor
Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma	2013/11/21	NCT01989598	Phase 2	Completed	National Cancer Institute (NCI)
Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma	2013/11/08	NCT01979523	Phase 2	Completed	National Cancer Institute (NCI)
GSK1120212+GSK2141795 for Cervical Cancer	2013/10/08	NCT01958112	Phase 2	Terminated	Dana-Farber Cancer Institute
Trametinib With GSK2141795 in BRAF Wild-type Melanoma	2013/09/13	NCT01941927	Phase 2	Completed	Adil Daud
Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer	2013/09/05	NCT01935973	Phase 1	Completed	National Cancer Institute (NCI)
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer	2013/07/18	NCT01902173	Phase 1	Completed	National Cancer Institute (NCI)
An Open Label Study To Investigate the Pharmacokinetics and Pharmacodynamics of Repeat Escalating Doses of the Oral AKT Inhibitor GSK2141795 by 18F FDG PET Analysis in Subjects With Ovarian Cancer	2010/12/24	NCT01266954	Phase 1	Completed	GlaxoSmithKline
Safety, Pharmacokinetics (PK) of AKT and MEK Combination	2010/06/07	NCT01138085	Phase 1	Completed	GlaxoSmithKline
A Phase I, Open-Label, First-Time-In-Human Study of the Oral AKT Inhibitor GSK2141795	2009/06/15	NCT00920257	Phase 1	Completed	GlaxoSmithKline

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
No HSA approvals found for this drug.

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
No TGA approvals found for this drug.

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