Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Magnesium Sulfate for Fetal Neuroprotection
- First Posted Date
- 2020-05-26
- Last Posted Date
- 2021-02-09
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 200
- Registration Number
- NCT04401852
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Improving Quality of Bier Block
- First Posted Date
- 2020-05-19
- Last Posted Date
- 2020-05-21
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 75
- Registration Number
- NCT04393610
- Locations
- 🇪🇬
Assiut University Hospital, Assiut, Egypt
Levosimendan Versus Combination With Magnesium Sulphate on Spine Protection by NIRS in Infants Undergoing Coarctectomy
- Conditions
- Interventions
- First Posted Date
- 2020-04-01
- Last Posted Date
- 2023-10-16
- Lead Sponsor
- Dalia Saad Abd-El Kader
- Target Recruit Count
- 40
- Registration Number
- NCT04330755
- Locations
- 🇪🇬
Sara ABD El-Salam, Cairo, Egypt
Magnesium Sulfate Versus Dexmedetomidine on Anesthesia Awakening.
- Conditions
- Interventions
- First Posted Date
- 2020-03-09
- Last Posted Date
- 2023-01-11
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT04300985
- Locations
- 🇧🇷
Hospital das Clínicas - Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil
Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
- First Posted Date
- 2020-02-19
- Last Posted Date
- 2022-04-19
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT04275661
- Locations
- 🇪🇬
south Egypt Cancer Institute Assiut University, Assiut, Egypt
Effect of Intraoperative Magnesium Infusion on Postoperative Pain and Cognitive Function
- First Posted Date
- 2020-02-05
- Last Posted Date
- 2020-02-05
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 24
- Registration Number
- NCT04256057
- Locations
- 🇪🇬
Faculty of Medicine, Beni-SuefUniversity, Giza, Egypt
🇪🇬Beni-Suef University Hospital, Banī Suwayf, Egypt
🇪🇬Faculty of Medicine,Beni-Suef University, Giza, Egypt
Prevention of Post-Operative Cardiac Arrhythmias
- First Posted Date
- 2020-01-21
- Last Posted Date
- 2022-03-15
- Lead Sponsor
- Jeffrey Moak
- Target Recruit Count
- 870
- Registration Number
- NCT04234906
Effects of Intraoperative Magnesium Sulfate on Perioperative Pain Relief After Spine Surgery
- Conditions
- Interventions
- First Posted Date
- 2019-11-13
- Last Posted Date
- 2020-05-14
- Lead Sponsor
- Aristotle University Of Thessaloniki
- Target Recruit Count
- 74
- Registration Number
- NCT04161729
- Locations
- 🇬🇷
AHEPA University Hospital, Thessaloniki, Greece
Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
- Conditions
- Interventions
- First Posted Date
- 2019-07-09
- Last Posted Date
- 2020-12-24
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 68
- Registration Number
- NCT04013243
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level
- Conditions
- Interventions
- First Posted Date
- 2019-04-26
- Last Posted Date
- 2021-04-23
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 400
- Registration Number
- NCT03928691
- Locations
- 🇪🇬
Ahmed Abbas, Assiut, Cairo, Egypt
Drug Development Updates
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