Overview
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Associated Conditions
- Nausea
- Nausea and vomiting
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2015/02/26 | Phase 1 | Completed | |||
2014/10/13 | Phase 1 | Completed | |||
2013/01/17 | Phase 4 | Completed | MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals | ||
2007/06/21 | Phase 4 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Sun Pharmaceutical Industries, Inc. | 53489-376 | ORAL | 300 mg in 1 1 | 11/17/2017 | |
| Physicians Total Care, Inc. | 54868-5741 | ORAL | 300 mg in 1 1 | 8/24/2010 | |
| Direct_Rx | 61919-884 | ORAL | 300 mg in 1 1 | 1/12/2023 | |
| Rebel Distributors Corp | 21695-853 | INTRAMUSCULAR | 100 mg in 1 mL | 6/17/2009 | |
| Chartwell RX, LLC | 62135-773 | ORAL | 300 mg in 1 1 | 11/27/2023 | |
| HF Acquisition Co LLC, DBA HealthFirst | 51662-1430 | INTRAMUSCULAR | 100 mg in 1 mL | 1/28/2024 | |
| Lupin Pharmaceuticals,Inc. | 43386-660 | ORAL | 300 mg in 1 1 | 1/30/2024 | |
| Bryant Ranch Prepack | 63629-3685 | ORAL | 300 mg in 1 1 | 11/17/2017 | |
| Henry Schein, Inc | 0404-9964 | INTRAMUSCULAR | 100 mg in 1 mL | 11/14/2023 | |
| General Injectables & Vaccines, Inc | 52584-119 | INTRAMUSCULAR | 100 mg in 1 mL | 12/27/2022 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| No Health Canada approvals found for this drug. | |||||
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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