Ajmaline
- Generic Name
- Ajmaline
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C20H26N2O2
- CAS Number
- 4360-12-7
- Unique Ingredient Identifier
- 1PON08459R
- Background
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments. T...
- Indication
对各种室上性及室性心律失常均有效，对预激综合征伴发的室上性心动过速、房颤、房扑，其有效率可达80％～90％。对室上性心动过速复律效果也佳。
- Associated Conditions
- Symptomatic Supraventricular Tachycardia, Tachycardia, Ectopic Junctional, Ventricular Tachycardia (VT)
- Associated Therapies
- Persistent Ventricula
Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial
- Conditions
- Interventions
- First Posted Date
- 2020-10-09
- Last Posted Date
- 2021-12-08
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 25
- Registration Number
- NCT04580992
- Locations
- 🇧🇪
UZ Brussels, Jette, Brussel, Belgium
The Response To Ajmaline Provocation in Healthy Subjects
- First Posted Date
- 2016-10-14
- Last Posted Date
- 2019-11-05
- Lead Sponsor
- St George's, University of London
- Target Recruit Count
- 100
- Registration Number
- NCT02933437
- Locations
- 🇬🇧
St George's University Of London, London, United Kingdom
Epicardial Ablation in Brugada Syndrome
- Conditions
- Interventions
- First Posted Date
- 2015-12-29
- Last Posted Date
- 2018-01-17
- Lead Sponsor
- IRCCS Policlinico S. Donato
- Target Recruit Count
- 135
- Registration Number
- NCT02641431
- Locations
- 🇮🇹
IRCCS Policlinico S. Donato, San Donato Milanese, Milano, Italy
Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias
- Conditions
- Interventions
- First Posted Date
- 2008-06-20
- Last Posted Date
- 2010-12-15
- Lead Sponsor
- Hospital Clinic of Barcelona
- Target Recruit Count
- 123
- Registration Number
- NCT00702117
- Locations
- 🇪🇸
Hospital Puerta de Hierro, Madrid, Spain
🇪🇸Hospital Donostia, Donostia, Guipuzcoa, Spain
🇪🇸Hospital La Fe, Valencia, Spain
Drug Development Updates
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