Telbivudine
- Generic Name
- Telbivudine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C10H14N2O5
- CAS Number
- 3424-98-4
- Unique Ingredient Identifier
- 2OC4HKD3SF
- Background
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
- Indication
For the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
- Associated Conditions
- Chronic Hepatitis B Infection
- Associated Therapies
- -
Telbivudine Versus Lamivudine in Chinese Adults With Compensated Chronic Hepatitis B
Phase 3
Completed
- Conditions
- First Posted Date
- 2005-08-19
- Last Posted Date
- 2015-05-12
- Lead Sponsor
- Novartis
- Registration Number
- NCT00131742
Telbivudine Versus the Combination of Telbivudine and Valtorcitabine in Patients With Chronic Hepatitis B
Phase 2
Completed
- Conditions
- First Posted Date
- 2005-08-10
- Last Posted Date
- 2017-06-16
- Lead Sponsor
- Novartis
- Target Recruit Count
- 130
- Registration Number
- NCT00128544
An Extension Study of Telbivudine, Lamivudine or Telbivudine Plus Lamivudine in Patients With Chronic Hepatitis B
Phase 2
Completed
- Conditions
- First Posted Date
- 2005-07-27
- Last Posted Date
- 2015-05-12
- Lead Sponsor
- Novartis
- Registration Number
- NCT00124241
Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2004-01-22
- Last Posted Date
- 2011-09-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 232
- Registration Number
- NCT00076336
- Locations
- 🇻🇳
Novartis, Hanoi, Vietnam
Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients With Both HBV and HIV
Not Applicable
Withdrawn
- Conditions
- Interventions
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