Gadopentetic acid

Generic Name
Gadopentetic acid
Brand Names
Magnevist
Drug Type
Small Molecule
Chemical Formula
C14H20GdN3O10
CAS Number
80529-93-7
Unique Ingredient Identifier
K2I13DR72L
Background

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)

Indication

For use with magnetic resonance imaging (MRI) in adults, and pediatric patients (2 years of age and older) to visualize lesions with abnormal vascularity in the brain (intracranial lesions), spine and associated tissues as well as lesions with abnormal vascularity in the head and neck. Also used to facilitate the visualization of lesions with abnormal vascul...

Associated Conditions
-
Associated Therapies
-

Gadolinium-Based-Contrast-Agents (GBCA) Enhancement During MR Urography

First Posted Date
2019-04-10
Last Posted Date
2019-04-10
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
500
Registration Number
NCT03910114
Locations
🇺🇸

Vanderbilt Childeen's Hospital, Nashville, Tennessee, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

First Posted Date
2014-10-30
Last Posted Date
2017-03-31
Lead Sponsor
Michael Vogelbaum, MD, PhD
Target Recruit Count
3
Registration Number
NCT02278510
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis

First Posted Date
2013-10-08
Last Posted Date
2016-02-04
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
80
Registration Number
NCT01956409
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Multihance Versus Magnevist in Breast MRI

Phase 3
Completed
Conditions
First Posted Date
2007-06-14
Last Posted Date
2010-07-15
Lead Sponsor
Bracco Diagnostics, Inc
Target Recruit Count
130
Registration Number
NCT00486473

Crossover Study With MultiHance vs a Comparator for Peripheral MRA

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-12-06
Last Posted Date
2009-03-27
Lead Sponsor
Bracco Diagnostics, Inc
Target Recruit Count
100
Registration Number
NCT00408083
Locations
🇮🇹

Bracco Imaging, Milan, Italy

Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients

First Posted Date
2006-11-03
Last Posted Date
2015-06-08
Lead Sponsor
Bayer
Target Recruit Count
147
Registration Number
NCT00395460
Locations
🇨🇳

Fudan University Huashan Hospital, Shanghai, China

🇨🇳

Jiangsu Province Hospital, Nanjing, Jiangsu, China

🇨🇳

The 1st Affiliated Hosp of the 4th Military Med Uni, Xi'an, Shaanxi, China

and more 1 locations
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