MedPath

Blu-5937

Generic Name
Blu-5937

A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age

Phase 1
Completed
Conditions
Cough
Interventions
First Posted Date
2024-01-25
Last Posted Date
2025-03-07
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
21
Registration Number
NCT06222892
Locations
🇺🇸

GSK Investigational Site, San Antonio, Texas, United States

Evaluation of the Pharmacokinetics and Safety of BLU-5937 in Healthy Adult Japanese and Caucasian Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2023-12-22
Last Posted Date
2023-12-22
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
34
Registration Number
NCT06179537
Locations
🇬🇧

Richmond Pharmacology Ltd., London, United Kingdom

Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant

Phase 1
Completed
Conditions
Cough
Healthy
Interventions
First Posted Date
2023-07-25
Last Posted Date
2025-03-26
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
45
Registration Number
NCT05959447
Locations
🇨🇦

GSK Investigational Site, Quebec City, Quebec, Canada

Evaluation of the Effect of Rifampin and Rabeprazole on the Pharmacokinetics of Camlipixant

Phase 1
Completed
Conditions
Cough
Healthy
Interventions
First Posted Date
2023-06-12
Last Posted Date
2024-12-04
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
42
Registration Number
NCT05899829
Locations
🇨🇦

GSK Investigational Site, Quebec City, Quebec, Canada

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Phase 3
Recruiting
Conditions
Refractory Chronic Cough
Interventions
Drug: Placebo
First Posted Date
2022-10-31
Last Posted Date
2024-02-15
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
825
Registration Number
NCT05599191
Locations
🇺🇸

Remington-Davis, Inc., Columbus, Ohio, United States

🇺🇸

Well Pharma Medical Research Corporation, Miami, Florida, United States

🇿🇦

Dr JM Engelbrecht Trial Site, Somerset West, Western Cape, South Africa

and more 179 locations

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (CALM-2)

Phase 3
Recruiting
Conditions
Refractory Chronic Cough
Interventions
Drug: Placebo
First Posted Date
2022-10-31
Last Posted Date
2024-02-15
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
825
Registration Number
NCT05600777
Locations
🇮🇳

Government Hospital for Chest and Communicable Diseases, Visakhapatnam, Andhra Pradesh, India

🇺🇸

In-Quest Medical Research, LLC, Norcross, Georgia, United States

🇺🇸

Geisinger Medical Center, Danville, Pennsylvania, United States

and more 96 locations

A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis

Phase 2
Completed
Conditions
Chronic Pruritus
Atopic Dermatitis
Interventions
Drug: Placebo
First Posted Date
2021-01-05
Last Posted Date
2022-10-17
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
142
Registration Number
NCT04693195
Locations
🇺🇸

Bellus Health Investigational Site #29, Norman, Oklahoma, United States

🇺🇸

Bellus Health Investigational Site #25, Seattle, Washington, United States

🇺🇸

Bellus Health Investigational Site #15, Hialeah, Florida, United States

and more 30 locations

Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Phase 2
Completed
Conditions
Refractory Chronic Cough
Interventions
Drug: Placebo
First Posted Date
2020-12-21
Last Posted Date
2021-12-13
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
310
Registration Number
NCT04678206
Locations
🇺🇸

Montana Medical Research, Missoula, Montana, United States

🇨🇦

Diex Recherche - Québec, Québec, Quebec, Canada

🇨🇦

Inspiration Research Limited, Toronto, Quebec, Canada

and more 112 locations

A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough

Phase 2
Terminated
Conditions
Chronic Refractory Cough
Interventions
Drug: Placebo
First Posted Date
2019-06-07
Last Posted Date
2021-08-03
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
68
Registration Number
NCT03979638
Locations
🇺🇸

Allergy Asthma & Sinus Center, Greenfield, Wisconsin, United States

🇺🇸

Clinical Research of Gastonia, Gastonia, North Carolina, United States

🇬🇧

Prince Phillip Hospital, Llanelli, United Kingdom

and more 13 locations

BLU-5937: First-in-Human, Single and Multiple Doses Escalation, Safety, Tolerability, Pharmacokinetics and Food Effect

Phase 1
Completed
Conditions
Cough
Interventions
Drug: Placebo
First Posted Date
2018-08-20
Last Posted Date
2018-11-09
Lead Sponsor
Bellus Health Inc. - a GSK company
Target Recruit Count
90
Registration Number
NCT03638180
Locations
🇨🇦

Alta Sciences Algorithme Pharma, Mount-Royal, Quebec, Canada

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