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Sucralfate

Generic Name
Sucralfate
Brand Names
Carafate, Sulcrate
Drug Type
Small Molecule
Chemical Formula
C12H35Al9O55S8
CAS Number
54182-58-0
Unique Ingredient Identifier
XX73205DH5

Overview

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers , gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in the gastrointestinal tract from damage caused by agents such as gastric acid, bile salts, alcohol, and acetylsalicylic acid (aspirin), among other substances . Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms. It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form .

Background

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers , gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in the gastrointestinal tract from damage caused by agents such as gastric acid, bile salts, alcohol, and acetylsalicylic acid (aspirin), among other substances . Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms. It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form .

Indication

The sucralfate suspension and tablet are used for the treatment of active duodenal ulcer for up to 8 weeks. The tablet form may be used at a lower dose for healed duodenal ulcers, for the purpose of maintaining healing and preventing recurrence . Sucralfate is also used in the prevention and/or treatment of gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia .

Associated Conditions

  • Dyspepsia
  • Gastric Ulcer
  • Gastritis
  • Gastro-esophageal Reflux Disease (GERD)
  • Healing
  • Mucositis
  • Peptic Ulcer
  • Stress Ulcers
  • Active Duodenal ulcer

FDA Approved Products

Sucralfate
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:1 g in 1 1
Approved: 2024/02/23
NDC:72162-2264
SUCRALFATE
Manufacturer:H.J. Harkins Company, Inc.
Route:ORAL
Strength:1 g in 1 1
Approved: 2018/08/21
NDC:76519-1025
Sucralfate
Manufacturer:American Health Packaging
Route:ORAL
Strength:1 g in 1 1
Approved: 2023/01/25
NDC:60687-695
Sucralfate
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:1 g in 1 1
Approved: 2021/05/19
NDC:71610-541
Sucralfate
Manufacturer:Teva Pharmaceuticals USA, Inc.
Route:ORAL
Strength:1 g in 1 1
Approved: 2015/09/30
NDC:0093-2210

Singapore Approved Products

APO-SUCRALFATE TABLET 1 g
Manufacturer:APOTEX INC
Form:TABLET
Strength:1 g
Online:Yes
Approved: 1996/02/27
Approval:SIN08585P

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